Au Wing-Kuk, Chiu Shiu-Wah, Sun Man-Ping, Cheung Lik-Ching, Cheng Lik-Cheung
Department of Surgery, University of Hong Kong, Grantham Hospital, Hong Kong, People's Republic of China.
Asian Cardiovasc Thorac Ann. 2003 Sep;11(3):222-5. doi: 10.1177/021849230301100309.
Between October 1999 and December 2000, 52 patients (37 male) undergoing coronary artery bypass surgery were selected for overdrive biatrial pacing to determine its effectiveness in reducing atrial fibrillation. A pacing wire was attached to the right atrial appendage and another to the roof of the left atrium behind the aorta. The atria were paced continuously in AAI mode at a rate of 90 pulses per minute or 10 pulses above the underlying rate (maximum rate < 140/min) for 3 days. The endpoint was the onset of atrial fibrillation during hospital stay. Results were compared with those of a control group of 52 matched patients. There were no significant differences in the occurrence of atrial fibrillation (30% in the paced group vs. 25% in the control group), morbidity, or length of hospital stay. Continuous biatrial pacing after coronary bypass surgery was safe and well tolerated, however, it did not prevent or lower the incidence of atrial fibrillation.
1999年10月至2000年12月期间，52例接受冠状动脉搭桥手术的患者（37例男性）被选入超速双房起搏研究，以确定其在减少房颤方面的有效性。一根起搏导线连接到右心耳，另一根连接到主动脉后方左心房顶部。心房以AAI模式持续起搏，频率为每分钟90次脉冲或比基础心率高10次脉冲（最大心率<140次/分钟），持续3天。终点指标是住院期间房颤的发作。将结果与52例匹配的对照组患者进行比较。在房颤发生率（起搏组为30%，对照组为25%）、发病率或住院时间方面没有显著差异。冠状动脉搭桥手术后持续双房起搏是安全的且耐受性良好，然而，它并不能预防或降低房颤的发生率。
