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[短时间有规律地暴露于脉冲电场期间大脑生物电活动的一些变化]

[Some changes in bioelectrical activity of the brain during short regulated exposure to pulsed electrical fields].

作者信息

Pestriaev V A

机构信息

Ural State Medical Academy, ul. Repina 3, Ekaterinburg, 620219 Russia.

出版信息

Biofizika. 2003 Jul-Aug;48(4):733-9.

PMID:14515495
Abstract

It was shown that short (10 s) exposures of white rats being at rest to impulse (1 ms) electromagnetic fields (170 A/m) at a fixed frequency of pulse sequence in the range of the theta-rhythm do not change the contribution to the electrocorticogram (ECoG) of the harmonic whose frequency corresponds to the frequency of pulse sequence. By contrast, treatments with a frequency-pulse modulation at which the interpulse intervals corresponding to the frequency of the harmonic being studied were not observed throughout the range of exposure but at which their high correlation was provided, assisted in decreasing the contribution of the harmonic to the ECoG spectrum. If the functional state of the central nervous system was changed by drugs leading to the predominance of the short-wavelength activity in the ECoG, both regimes of exposure significantly affected the contribution of the harmonic in the ECoG, whose direction and dynamics depended on the excitability of neurons.

摘要

结果表明,处于静息状态的白鼠在θ节律范围内以固定脉冲序列频率暴露于脉冲(1毫秒)电磁场(170安/米)10秒,不会改变频率与脉冲序列频率相对应的谐波对脑电图(ECoG)的贡献。相比之下,采用频率脉冲调制处理,在整个暴露范围内未观察到与所研究谐波频率相对应的脉冲间隔,但提供了它们的高度相关性,这有助于降低谐波对ECoG频谱的贡献。如果通过药物改变中枢神经系统的功能状态,导致ECoG中短波长活动占主导,两种暴露方式都会显著影响谐波在ECoG中的贡献,其方向和动态取决于神经元的兴奋性。

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