Iskandar Said B, Dittus Kim, Merrick Dan
Veterans Affairs Medical Center, Mountain Home, TN, USA.
South Med J. 2003 Aug;96(8):828-31. doi: 10.1097/01.SMJ.0000077068.61831.7A.
Myocardial infarction is a common life-threatening condition. Multiple agents can be used to treat acute coronary syndrome (ACS). These therapeutic agents pose potential life-threatening complications when used outside the realm of the acute coronary syndrome. Hypertrophic cardiomyopathy (HCM) is a common inherited cardiac disorder, occurring in 1 in 500 individuals, which may mimic ACS. The hypertrophy most typically involves the septum in patients with HCM. As many as 25% of Japanese patients with HCM have predominately apical involvement. Apical hypertrophic cardiomyopathy (AHC) occurs in only 1 to 2% of the non-Japanese population. Despite its low incidence, physicians caring for patients with chest pain need to consider AHC in their differential diagnosis. We present the case of a patient with chest pain and electrocardiographic changes suggestive of ACS who was later found to have AHC.
心肌梗死是一种常见的危及生命的病症。多种药物可用于治疗急性冠状动脉综合征（ACS）。这些治疗药物在急性冠状动脉综合征范围之外使用时会带来潜在的危及生命的并发症。肥厚型心肌病（HCM）是一种常见的遗传性心脏疾病，每500人中就有1人患病，它可能会模仿急性冠状动脉综合征。肥厚在肥厚型心肌病患者中最典型地累及室间隔。多达25%的日本肥厚型心肌病患者主要是心尖受累。心尖肥厚型心肌病（AHC）仅发生在1%至2%的非日本人群中。尽管其发病率较低，但照顾胸痛患者的医生在鉴别诊断时需要考虑心尖肥厚型心肌病。我们报告了一例胸痛且心电图改变提示急性冠状动脉综合征的患者，该患者后来被发现患有心尖肥厚型心肌病。
