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青少年患者拇籽骨孤立性骨内痛风酷似骨肿瘤

Isolated intraosseous gout in hallux sesamoid mimicking a bone tumor in a teenaged patient.

作者信息

Liu Shi-Zuo, Yeh LeeRen, Chou Yi-Jiun, Chen Clement Kuen-Huang, Pan Huay-Ban

机构信息

Department of Radiology, Kaohsiung Veterans General Hospital, 386 Ta-Chung first Rd., 813 Kaohsiung, Taiwan, ROC.

出版信息

Skeletal Radiol. 2003 Nov;32(11):647-50. doi: 10.1007/s00256-003-0692-3. Epub 2003 Sep 27.

Abstract

We are reporting an unusual case of isolated intraosseous tophus in medial hallux sesamoid presenting as tumor-like lesion in a teenage patient without prior history of gouty attack and underlying systemic disorders. The lesion manifested isointensity to surrounding muscles with internal low signal on spin echo (SE) T1-weighted images, and heterogeneous low signal intensity on fast spin echo (FSE) T2-weighted images. Computed tomography (CT) scan disclosed expansion and diffusely increased attenuation of the medial hallux sesamoid with focal cortical erosion and extraosseous extension of high attenuation content. The subsequent resection and pathology revealed intraosseous tophus deposition, which is particularly rare at this site and at this age. Imaging studies revealed some characteristic imaging features which can retrospectively be attributed to gouty tophus. When an expansile osteolytic lesion manifesting low signal intensity on T2-weighted image and internal calcifications on CT scan is encountered, the possibility of intraosseous tophus should be included in the list of differential diagnoses, even in a teenage patient without prior history of gout.

摘要

我们报告了一例罕见病例,一名青少年患者的内侧拇籽骨出现孤立性骨内痛风石,表现为肿瘤样病变,该患者既往无痛风发作史及潜在的全身性疾病。在自旋回波(SE)T1加权图像上,该病变表现为与周围肌肉等信号,内部呈低信号;在快速自旋回波(FSE)T2加权图像上,表现为不均匀的低信号强度。计算机断层扫描(CT)显示内侧拇籽骨膨胀,密度弥漫性增加,伴有局灶性皮质侵蚀和高密度内容物的骨外延伸。随后的切除及病理检查显示为骨内痛风石沉积,这在该部位和这个年龄段尤为罕见。影像学研究显示了一些特征性的影像学表现,这些表现可追溯到痛风石。当遇到在T2加权图像上表现为低信号强度且CT扫描显示内部有钙化的膨胀性溶骨性病变时,即使是没有痛风病史的青少年患者,骨内痛风石的可能性也应列入鉴别诊断清单中。

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