Gold Garry E, McCauley Thomas R, Gray Martha L, Disler David G
Department of Radiology, Stanford University, Packard EE Bldg, Rm 222, Stanford, CA 94305-9510, USA.
Radiographics. 2003 Sep-Oct;23(5):1227-42. doi: 10.1148/rg.235035113.
Magnetic resonance (MR) imaging of articular cartilage is important in evaluation of new surgical and pharmacologic treatments for cartilage damage. Many techniques exist for MR imaging of articular cartilage. Standard techniques for morphologic imaging of cartilage include fast spin-echo and spoiled gradient-echo imaging. These methods provide high-resolution morphologic images of cartilage but are time-consuming in the clinical setting. New methods for faster or higher-resolution morphologic imaging include techniques based on steady-state free precession imaging. These fast techniques will allow detailed evaluation of cartilage in the routine clinical setting. There are also several MR imaging methods that may provide information about the structure and physiology of cartilage. Physiologic imaging may allow detailed evaluation of the glycosaminoglycan matrix or collagen network of articular cartilage and may be the most sensitive method for detection of early changes. With the development of new therapies for osteoarthritis and cartilage injury, MR imaging of articular cartilage is of increasing clinical importance. MR imaging will play an important role in evaluation of the effectiveness of these therapies.
关节软骨的磁共振（MR）成像对于评估软骨损伤的新型手术和药物治疗至关重要。存在多种用于关节软骨MR成像的技术。软骨形态学成像的标准技术包括快速自旋回波和扰相梯度回波成像。这些方法可提供软骨的高分辨率形态学图像，但在临床环境中耗时较长。用于更快或更高分辨率形态学成像的新方法包括基于稳态自由进动成像的技术。这些快速技术将允许在常规临床环境中对软骨进行详细评估。还有几种MR成像方法可能提供有关软骨结构和生理学的信息。生理学成像可允许对关节软骨的糖胺聚糖基质或胶原网络进行详细评估，并且可能是检测早期变化的最敏感方法。随着骨关节炎和软骨损伤新疗法的发展，关节软骨的MR成像在临床上的重要性日益增加。MR成像将在评估这些疗法的有效性方面发挥重要作用。
