Yoh Kiyotaka, Kubota Kaoru, Nomura Masanobu, Niho Seiji, Goto Koichi, Ohmatsu Hironobu, Kakinuma Ryutaro, Nishiwaki Yutaka
Thoracic Oncology Division, National Cancer Center Hospital East, Kashiwa, Chiba.
Intern Med. 2003 Sep;42(9):831-3. doi: 10.2169/internalmedicine.42.831.
Paraneoplastic Cushing's syndrome caused by ectopic adrenocorticotropin production has been reported in association with a variety of malignant tumors. However, most cases of this syndrome are associated with neuroendocrine tumors such as small-cell lung cancer (SCLC), carcinoid tumors, and medullary carcinoma of the thyroid. We present a 49-year-old man who developed Cushing's syndrome associated with adenocarcinoma of the lung. He had a wide variety of clinical symptoms and comorbidity related to this syndrome during the course, and died 4 months after the diagnosis. This is a very rare case report of Cushing's syndrome associated with adenocarcinoma of the lung.
由异位促肾上腺皮质激素分泌引起的副肿瘤性库欣综合征已被报道与多种恶性肿瘤相关。然而,该综合征的大多数病例与神经内分泌肿瘤有关,如小细胞肺癌(SCLC)、类癌肿瘤和甲状腺髓样癌。我们报告一名49岁男性,他患上了与肺腺癌相关的库欣综合征。在此过程中,他出现了与该综合征相关的多种临床症状和合并症,并在诊断后4个月死亡。这是一例与肺腺癌相关的库欣综合征的非常罕见的病例报告。