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青少年原发性甲状腺功能减退症伴高催乳素血症、巨大垂体增大的原发性闭经-溢乳

Primary amenorrhea-galactorrhea with hyperprolactinemia and huge pituitary enlargement in juvenile primary hypothyroidism.

作者信息

Chaieb L, Chadli-Chaieb M, Chaieb A, Zebidi A, Allegue M

机构信息

Endocrine-Metabolic Service, Farhat Hached Hospital, Sousse, Tunisia.

出版信息

Eur J Obstet Gynecol Reprod Biol. 1992 Sep 23;46(2-3):159-62. doi: 10.1016/0028-2243(92)90264-y.

Abstract

We report a girl with juvenile primary hypothyroidism revealed by growth retardation and a syndrome of primary amenorrhea-galactorrhea with hyperprolactinemia and suprasellar pituitary enlargement. Resolution of the pituitary enlargement and the amenorrhea-galactorrhea syndrome occurred after thyroid hormone replacement. No similar observation has been reported earlier in juvenile hypothyroidism.

摘要

我们报告了一名患有青少年原发性甲状腺功能减退症的女孩,该病症由生长发育迟缓以及原发性闭经 - 溢乳综合征伴高催乳素血症和鞍上垂体增大所揭示。甲状腺激素替代治疗后,垂体增大以及闭经 - 溢乳综合征得到缓解。此前在青少年甲状腺功能减退症中尚未有类似的观察报告。

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