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原发性甲状腺功能减退患者中，甲状腺素对高催乳素血症性溢乳-闭经及蝶鞍异常的临床、生化和影像学可逆性。

Clinical, biochemical, and radiologic reversibility of hyperprolactinemic galactorrhea-amenorrhea and abnormal sella by thyroxine in a patient with primary hypothyroidism.

作者信息

Tolis G, Hoyte K, McKenzie J M, Mason B, Robb P

出版信息

Am J Obstet Gynecol. 1978 Aug 15;131(8):850-2. doi: 10.1016/s0002-9378(16)33129-5.

DOI:10.1016/s0002-9378(16)33129-5
PMID:567430
Abstract

A case of primary hypothyroidism associated with postpartum galactorrhea-amenorrhea is reported. The configuration of the sella was compatible with pituitary adenoma, but prolactin dynamics did not support an autonomous secretory state. Replacement therapy with thyroxine led to complete reversal of clinical, radiologic, and biochemical abnormalities.

摘要

报告了一例原发性甲状腺功能减退症合并产后溢乳-闭经的病例。蝶鞍形态与垂体腺瘤相符，但催乳素动态变化不支持自主分泌状态。甲状腺素替代治疗使临床、影像学和生化异常完全逆转。

相似文献

1
Clinical, biochemical, and radiologic reversibility of hyperprolactinemic galactorrhea-amenorrhea and abnormal sella by thyroxine in a patient with primary hypothyroidism.原发性甲状腺功能减退患者中，甲状腺素对高催乳素血症性溢乳-闭经及蝶鞍异常的临床、生化和影像学可逆性。
Am J Obstet Gynecol. 1978 Aug 15;131(8):850-2. doi: 10.1016/s0002-9378(16)33129-5.
2
Regression of pituitary tumor after thyroid replacement in primary hypothyroidism.原发性甲状腺功能减退症患者甲状腺替代治疗后垂体瘤消退
South Med J. 1983 Apr;76(4):529-31. doi: 10.1097/00007611-198304000-00036.
3
Primary hypothyroidism, amenorrhea, and galactorrhea.原发性甲状腺功能减退、闭经和溢乳。
Arch Intern Med. 1978 Sep;138(9):1411-2.
4
Amenorrhea-galactorrhea due to occult hypothyroidism.隐匿性甲状腺功能减退所致闭经-溢乳
South Med J. 1986 Sep;79(9):1183-4. doi: 10.1097/00007611-198609000-00041.
5
Prolactin-secreting pituitary adenomas. III. Frequency and diagnosis in amenorrhea-galactorrhea.分泌催乳素的垂体腺瘤。III. 闭经-溢乳综合征中的发生率及诊断
JAMA. 1980 Sep 19;244(12):1329-32. doi: 10.1001/jama.244.12.1329.
6
Amenorrhea-galactorrhea, hyperprolactinemia, and suprasellar pituitary enlargement as presenting features of primary hypothyroidism.闭经-溢乳、高催乳素血症及鞍上垂体增大作为原发性甲状腺功能减退症的表现特征。
Obstet Gynecol. 1984 Mar;63(3 Suppl):86S-89S.
7
Galactorrhea, amenorrhea, and hyperprolactinemia as manifestations of parasellar meningioma.溢乳、闭经和高催乳素血症作为鞍旁脑膜瘤的表现。
Arch Intern Med. 1980 Dec;140(12):1608-12.
8
The significance of galactorrhea in patients with normal menses, oligomenorrhea, and secondary amenorrhea.溢乳在月经正常、月经过少和继发性闭经患者中的意义。
Am J Obstet Gynecol. 1978 Apr 15;130(8):894-904. doi: 10.1016/0002-9378(78)90266-1.
9
Galactorrhea-amenorrhea due to primary hypothyroidism.原发性甲状腺功能减退所致溢乳-闭经
Am J Obstet Gynecol. 1973 Jul 1;116(5):661-5. doi: 10.1016/s0002-9378(15)33131-8.
10
Pituitary secretory reserve in patients with amenorrhea associated with galactorrhea.伴有溢乳的闭经患者的垂体分泌储备
Ann Endocrinol (Paris). 1974 Sep-Oct;35(5):535-45.

引用本文的文献

1
Pituitary thyrotroph hyperplasia mimicking prolactin-secreting adenoma.酷似催乳素分泌腺瘤的垂体促甲状腺激素细胞增生
J Endocrinol Invest. 1984 Aug;7(4):399-404. doi: 10.1007/BF03351025.
2
Idiopathic prolactin cell hyperplasia of the pituitary mimicking prolactin cell adenoma: a morphological study including immunocytochemistry, electron microscopy, and in situ hybridization.酷似催乳素细胞腺瘤的垂体特发性催乳素细胞增生：一项包括免疫细胞化学、电子显微镜检查和原位杂交的形态学研究
Acta Neuropathol. 1991;82(2):147-51. doi: 10.1007/BF00293958.