Webb Donna J, Brown Claire M, Horwitz Alan F
Department of Cell Biology, University of Virginia Health Sciences Center, Charlottesville, VA 22908, USA.
Curr Opin Cell Biol. 2003 Oct;15(5):614-20. doi: 10.1016/s0955-0674(03)00105-4.
Cell migration is a complex, tightly regulated process that involves the continuous formation and disassembly of adhesions. Despite the importance of these processes, very little is known about the factors that regulate adhesion dynamics during migration. Recent advances in imaging technologies are allowing monitoring of these processes during migration and are providing insight into the mechanisms that regulate them.
细胞迁移是一个复杂且受到严格调控的过程,涉及黏附的持续形成与解体。尽管这些过程很重要,但对于迁移过程中调节黏附动力学的因素却知之甚少。成像技术的最新进展使得在迁移过程中能够监测这些过程,并为调节它们的机制提供了深入了解。