Swift Steven E, Tate Susan B, Nicholas Joyce
Department of Obstetrics and Gynecology, Medical University of South Carolina, Charleston, SC 29425, USA.
Am J Obstet Gynecol. 2003 Aug;189(2):372-7; discussion 377-9. doi: 10.1067/s0002-9378(03)00698-7.
The purpose of this study was to evaluate the correlation between the symptoms of pelvic organ prolapse and the stage of support as determined by the pelvic organ prolapse quantification system.
Four hundred ninety-seven women who were seen for annual gynecologic examinations were recruited. Subjects underwent a pelvic examination and their degree of pelvic support was described according to the pelvic organ prolapse quantification system. They also completed a seven-question questionnaire regarding common symptoms of pelvic organ prolapse. Trend analysis was accomplished with linear regression.
Only 477 subjects correctly responded to the questionnaire. They were aged 18 to 82 years (mean age, 44 years). Forty-seven percent were white, 52% were African American, and 1% were of another racial group. The number of subjects with the various pelvic organ prolapse quantification stages were stage 0 (18 subjects), stage I (214 subjects), stage II (231 subjects), and stage III (14 subjects). No subject had stage IV prolapse. The average number of positive responses per subject for the symptoms was 0.27 for stage 0, 0.55 for stage I, 0.77 for stage II, and 2.1 for stage III. This trend did not attain statistical significance. The correlation of symptoms with the leading edge of the prolapse revealed that the average number of symptoms that were reported per subject increased from <1 to >1 when the leading edge of the prolapse extended beyond the hymenal remnants. This trend was statistically significant.
Women with pelvic organ prolapse with the leading edge of the prolapse beyond the hymenal remnants (some stage II and all stage III) have increased symptoms, which may help define symptomatic pelvic organ prolapse.
本研究旨在评估盆腔器官脱垂症状与盆腔器官脱垂量化系统所确定的支撑阶段之间的相关性。
招募了497名接受年度妇科检查的女性。受试者接受盆腔检查，并根据盆腔器官脱垂量化系统描述其盆腔支撑程度。她们还完成了一份关于盆腔器官脱垂常见症状的七项问卷。采用线性回归进行趋势分析。
只有477名受试者正确回答了问卷。她们年龄在18至82岁之间（平均年龄44岁）。47%为白人，52%为非裔美国人，1%为其他种族。处于不同盆腔器官脱垂量化阶段的受试者数量分别为：0期（18名受试者）、I期（214名受试者）、II期（231名受试者）和III期（14名受试者）。没有受试者处于IV期脱垂。各阶段受试者症状阳性反应的平均数量分别为：0期0.27、I期0.55、II期0.77、III期2.1。这一趋势未达到统计学显著性。症状与脱垂前沿的相关性显示，当脱垂前沿超出处女膜残端时，每名受试者报告的症状平均数量从<1增加到>1。这一趋势具有统计学显著性。
脱垂前沿超出处女膜残端的盆腔器官脱垂女性（部分II期和所有III期）症状增多，这可能有助于定义有症状的盆腔器官脱垂。
