Hui Chee-Kin, Lai Kam-Chuen, Yuen Man-Fung, Ng Matthew, Chan Chi-Kuen, Hu Wayne, Wong Wai-Man, Lai Ching-Lung, Wong Benjamin C Y
Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, China.
Gastrointest Endosc. 2003 Oct;58(4):500-4. doi: 10.1067/s0016-5107(03)01871-6.
The treatment of patients with bile duct stones and acute suppurative cholangitis is emergent biliary decompression either by endoscopic sphincterotomy, nasobiliary drainage, or stent insertion. The aim of this retrospective study was to determine whether endoscopic sphincterotomy, in addition to an internal endoprosthesis, improves outcome for patients with acute suppurative cholangitis.
A total of 74 patients with acute suppurative cholangitis and bile duct stones were included in the study; 37 had endoscopic sphincterotomy before insertion of plastic stent (Group 1), and 37 had a plastic stent inserted through an intact papilla (Group 2).
The success rates for stent insertion in Groups 1 and 2 were, respectively, 89.2% and 86.5% (p = 1.000). The complication rates in Group 1 and Group 2 were, respectively, 10.8% and 2.7% (p = 0.358). The median (interquartile range 25th-75th percentile) durations of hospital stay for patients in Group 1 and Group 2 were, respectively, 6.5 (4-11) days and 7 (5-12) days (p = 0.614). The median (interquartile range) lengths of time for resolution of jaundice in Group 1 and Group 2 were, respectively, 3 (2-6) days versus 4 (2-5) days (p = 0.981).
Endoscopic sphincterotomy, in addition to biliary stent insertion, is not required for successful biliary decompression in patients with severe acute cholangitis.
胆管结石合并急性化脓性胆管炎患者的治疗是通过内镜括约肌切开术、鼻胆管引流或支架置入进行紧急胆道减压。这项回顾性研究的目的是确定内镜括约肌切开术联合内置假体是否能改善急性化脓性胆管炎患者的治疗效果。
本研究共纳入74例急性化脓性胆管炎合并胆管结石患者;37例在置入塑料支架前接受了内镜括约肌切开术(第1组),37例通过完整的乳头置入塑料支架(第2组)。
第1组和第2组支架置入成功率分别为89.2%和86.5%(p = 1.000)。第1组和第2组的并发症发生率分别为10.8%和2.7%(p = 0.358)。第1组和第2组患者的中位住院时间(四分位间距,第25 - 75百分位数)分别为6.5(4 - 11)天和7(5 - 12)天(p = 0.614)。第1组和第2组黄疸消退的中位时间(四分位间距)分别为3(2 - 6)天和4(2 - 5)天(p = 0.981)。
对于重症急性胆管炎患者,成功的胆道减压并不需要在胆道支架置入之外进行内镜括约肌切开术。