Silverman Robert A, Stevenson Lori, Hastings Harold M
Department of Emergency Medicine, Long Island Jewish Medical Center, New Hyde Park, New York, NY 11040, USA.
Ann Emerg Med. 2003 Oct;42(4):577-86. doi: 10.1067/s0196-0644(03)00410-4.
Asthma morbidity is greater in younger patients. The reasons are not fully understood, although identifying demographic patterns of seasonality may help determine causes and potential prevention. The objective of this study is to determine the relationship between age and seasonal asthma periodicity in patients presenting to the emergency department (ED).
We conducted a retrospective study of ED visits from 1991 to 2000 in 11 municipal hospitals in New York City, with 911 receiving facilities. There were 673,141 patients who presented to the ED during the study period and had a primary diagnosis of acute asthma.
Distinct seasonal patterns were observed, with the highest number of visits occurring in the fall and the fewest in the summer. Seasonal fluctuations of ED visits were highest in children aged 13 years or younger (coefficient of variation [CV] 37.8%; 95% confidence interval [CI] 37.5% to 38.1%), with a peak in CV occurring at approximately age 7 years (CV 43.3%; 95% CI 43.0% to 43.6%). Less variability was noted with increasing age, and the population aged 30 years and older appeared to be the least susceptible to seasonal influences (CV 11.7%; 95% CI 11.3% to 12.1%). Although the total number of asthma visits decreased by more than 30% from 1991 to 2000, the CVs for each year remained within a relatively narrow range of 24.2% to 30.5%.
In an urban population, seasonal variability of asthma episodes requiring ED visits are closely linked to age, which may be important in understanding the causes of asthma and developing disease-management strategies for the prevention of asthma episodes.
哮喘发病率在年轻患者中更高。尽管识别季节性的人口统计学模式可能有助于确定病因和潜在的预防措施,但其中原因尚未完全明确。本研究的目的是确定急诊科就诊患者年龄与季节性哮喘周期性之间的关系。
我们对纽约市11家市立医院1991年至2000年的急诊科就诊情况进行了回顾性研究,这些医院有911个接收设施。在研究期间,有673141名患者到急诊科就诊,初步诊断为急性哮喘。
观察到明显的季节性模式,就诊次数最多的是秋季,最少的是夏季。13岁及以下儿童急诊科就诊的季节性波动最大(变异系数[CV]为37.8%;95%置信区间[CI]为37.5%至38.1%),CV峰值出现在大约7岁时(CV为43.3%;95%CI为43.0%至43.6%)。随着年龄增长,变异性降低,30岁及以上人群似乎对季节性影响最不敏感(CV为11.7%;95%CI为11.3%至12.1%)。尽管从1991年到2000年哮喘就诊总数下降了30%以上,但每年的CV仍保持在24.2%至30.5%的相对狭窄范围内。
在城市人群中,需要到急诊科就诊的哮喘发作的季节性变异性与年龄密切相关,这对于理解哮喘病因和制定预防哮喘发作的疾病管理策略可能很重要。