Naranjo Miguel A, Romero Carlos, Bellés José M, Montesinos Consuelo, Vicente Oscar, Serrano Ramón
Instituto de Biología Molecular y Celular de Plantas, Universidad Politécnica de Valencia-C.S.I.C., Camino de Vera s/n, 46022 Valencia, Spain.
Planta. 2003 Jul;217(3):417-24. doi: 10.1007/s00425-003-1017-4. Epub 2003 Mar 21.
Treatment of tobacco ( Nicotiana tabacum L.) plants with lithium induces the formation of necrotic lesions and leaf curling as in the case of incompatible pathogen interactions. Further similarities at the molecular level include accumulation of ethylene and of salicylic and gentisic acids, and induced expression of pathogenesis-related PR-P, PR5 and PR1 genes. With the exception of PR1 induction, lithium produced the same effects in transgenic tobacco plants that do not accumulate salicylate because of overexpression of the bacterial hydroxylase gene nahG. On the other hand, inhibition of ethylene biosynthesis with aminoethoxyvinylglycine prevented lithium-induced cell death and PR5 expression. These results suggest that lithium triggers a hypersensitive-like response where ethylene signalling is essential.
用锂处理烟草（Nicotiana tabacum L.）植株会诱导坏死斑的形成和叶片卷曲，这与不亲和病原体相互作用的情况类似。在分子水平上的进一步相似之处包括乙烯、水杨酸和龙胆酸的积累，以及病程相关蛋白PR-P、PR5和PR1基因的诱导表达。除了PR1的诱导外，锂在因细菌羟化酶基因nahG过表达而不积累水杨酸的转基因烟草植株中产生了相同的效应。另一方面，用氨基乙氧基乙烯基甘氨酸抑制乙烯生物合成可防止锂诱导的细胞死亡和PR5表达。这些结果表明，锂引发了一种类似过敏反应的应答，其中乙烯信号传导至关重要。
