Delaney T P, Uknes S, Vernooij B, Friedrich L, Weymann K, Negrotto D, Gaffney T, Gut-Rella M, Kessmann H, Ward E, Ryals J
Science. 1994 Nov 18;266(5188):1247-50. doi: 10.1126/science.266.5188.1247.
Transgenic tobacco and Arabidopsis thaliana expressing the bacterial enzyme salicylate hydroxylase cannot accumulate salicylic acid (SA). This defect not only makes the plants unable to induce systemic acquired resistance, but also leads to increased susceptibility to viral, fungal, and bacterial pathogens. The enhanced susceptibility extends even to host-pathogen combinations that would normally result in genetic resistance. Therefore, SA accumulation is essential for expression of multiple modes of plant disease resistance.
表达细菌酶水杨酸羟化酶的转基因烟草和拟南芥无法积累水杨酸（SA）。这一缺陷不仅使植物无法诱导系统获得性抗性，还导致其对病毒、真菌和细菌病原体的易感性增加。这种增强的易感性甚至延伸到通常会产生遗传抗性的宿主 - 病原体组合。因此，SA积累对于植物多种抗病模式的表达至关重要。
