[Observation of the morphological genesis of pleural mesothelioma induced by asbestos in rats].
作者信息
Wang C, Luo S, Liu X
出版信息
Hua Xi Yi Ke Da Xue Xue Bao. 1992 Jun;23(2):181-4.
PMID:1452154
Abstract
In order to observe the lesions of pleural mesothelia caused by asbestos, we injected asbestos fiber into the pleural cavity of Wistar rats. The result showed that there Was an obvious process for the morphological genesis of mesothelioma. Simple hyperplasia and stratified pleomorphic hyperplasia of mesothelial cells were found on the 30th and 106th day after the injection of asbestos fiber, respectively. The benign and malignant mesotheliomas were noted on the 300th day. Meanwhile, a two-way differentiation may be observed in the process of mesothelial hyperplasia.
摘要
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