爱沙尼亚癌症患者的自杀情况：一项基于人群的研究。
Suicides among cancer patients in Estonia: a population-based study.
作者信息
Innos K, Rahu K, Rahu M, Baburin A
机构信息
Department of Epidemiology and Biostatistics, Institute of Experimental and Clinical Medicine, Hiiu 42, 11619 Tallinn, Estonia.
出版信息
Eur J Cancer. 2003 Oct;39(15):2223-8. doi: 10.1016/s0959-8049(03)00598-7.
The objective of this study was to determine the suicide risk among cancer patients in Estonia. This risk was examined in a cohort of 65,419 persons diagnosed with cancer in 1983-1998. Standardised mortality ratios (SMR) were calculated using the suicide rates of the population of Estonia as a reference. During 192,078 person-years of follow-up between 1983 and 2000, 197 suicides occurred in the cohort. An increased suicide risk was found for men (SMR=1.73; 95% Confidence Interval (CI) 1.45-2.01), but not for women (SMR=0.50; 95% CI 0.37-0.66). Men had the highest risk 90-179 days following their diagnosis (SMR=4.27; 95% CI 2.81-6.21). During this time interval, among men, the risk was more pronounced for cancers of the oesophagus (SMR=35.63; 95% CI 9.71-91.22) and pancreas (SMR=14.53; 95% CI 1.76-52.50). This study provides further evidence that cancer is a risk factor for suicide, at least in men.
本研究的目的是确定爱沙尼亚癌症患者的自杀风险。在1983年至1998年被诊断患有癌症的65419人的队列中对这种风险进行了检测。以爱沙尼亚人口的自杀率为参照计算标准化死亡率（SMR）。在1983年至2000年的192078人年随访期间，该队列中有197例自杀事件发生。发现男性自杀风险增加（SMR = 1.73；95%置信区间（CI）为1.45 - 2.01），而女性没有（SMR = 0.50；95% CI为0.37 - 0.66）。男性在诊断后90 - 179天风险最高（SMR = 4.27；95% CI为2.81 - 6.21）。在此时间间隔内，男性中，食管癌（SMR = 35.63；95% CI为9.71 - 91.22）和胰腺癌（SMR = 14.53；95% CI为1.76 - 52.50）的风险更为明显。本研究提供了进一步的证据，证明癌症是自杀的一个风险因素，至少在男性中如此。
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