Damrongpipatkij Yudthsak, Bella Jonathan N, Gorski Robert, Heller Eliot N
Division of Cardiology, Department of Medicine, Bronx Lebanon Hospital Center, NY 10457, USA.
Med Sci Monit. 2003 Oct;9(10):MT107-11.
Left ventricular (LV) hypertrophy is an independent predictor of increased morbidity and mortality. However, whether assessment of LV mass and geometry by cardiac single photon emission computed tomography (SPECT) is feasible remains unclear.
MATERIAL/METHODS: We compared LV mass and geometry measured by cardiac SPECT to standard echocardiography in thirty consecutive patients (female 73%n mean age 22.64+/-17 years) who had both cardiac SPECT and echocardiography done less than 1 week apart.
There was good correlation between the LV mass (r=0.73, p <0.001) and relative wall thickness (r=0.50, p<0.01) derived by cardiac SPECT to those of standard echocardiography. Using Bland-Altman method, the 95% confident interval of agreement between cardiac SPECT and standard echocardiography ranged from -52 g (5th percentile) to 124 g (95th percentile, mean difference =36+/-45) for LV mass and from -1 (5th percentile) to -0.6 (95th percentile, mean difference =-0.8+/-0.1) for relative wall thickness.
Assessment of left ventricular mass and geometry using cardiac SPECT is feasible and may provide prognostic information beyond measurement of perfusion and function.
左心室肥厚是发病率和死亡率增加的独立预测因素。然而，通过心脏单光子发射计算机断层扫描（SPECT）评估左心室质量和几何形状是否可行仍不清楚。
材料/方法：我们比较了连续30例患者（女性占73%，平均年龄22.64±17岁）心脏SPECT测量的左心室质量和几何形状与标准超声心动图测量结果，这些患者在不到1周的时间内先后进行了心脏SPECT和超声心动图检查。
心脏SPECT得出的左心室质量（r=0.73，p<0.001）和相对室壁厚度（r=0.50，p<0.01）与标准超声心动图测量结果之间具有良好的相关性。采用Bland-Altman方法，心脏SPECT与标准超声心动图之间左心室质量的95%一致性置信区间为-52 g（第5百分位数）至124 g（第95百分位数，平均差值=36±45），相对室壁厚度的95%一致性置信区间为-1（第5百分位数）至-0.6（第95百分位数，平均差值=-0.8±0.1）。
使用心脏SPECT评估左心室质量和几何形状是可行的，并且可能提供除灌注和功能测量之外的预后信息。
