Myjak Przemysław, Nahorski Waclaw, Pietkiewicz Halina, von Nickisch-Rosenegk Markus, Stolarczyk Juliusz, Kacprzak Elzbieta, Felczak-Korzybska Iwona, Szostakowska Beata, Lucius Richard
Institute of Maritime and Tropical Medicine, Gdynia, Poland.
Clin Infect Dis. 2003 Oct 15;37(8):e121-5. doi: 10.1086/378296. Epub 2003 Sep 25.
Infections of humans with Echinococcus multilocularis, the causative agent of alveolar echinococcosis (AE), a zoonosis, have been described with increasing frequency in Poland since 1994. In the attempt to verify these reports, we analyzed specimens obtained from a representative group of Polish patients. Liver lesions in patients with AE that was diagnosed on the basis of results of histological and serological tests contained E. multilocularis DNA, as shown by the presence of specific microsatellite sequences and mitochondrial 12S rDNA. The same tests clearly distinguished between AE and cystic echinococcosis, which is caused by Echinococcus granulosus. These data are unequivocal proof that human infections with E. multilocularis occur in Poland.
自1994年以来，波兰境内人体感染多房棘球绦虫（泡型包虫病的病原体，一种人畜共患病）的病例报告日益增多。为核实这些报告，我们分析了从一组具有代表性的波兰患者身上获取的样本。根据组织学和血清学检测结果确诊为泡型包虫病的患者，其肝脏病变中含有多房棘球绦虫DNA，这可通过特定微卫星序列和线粒体12S rDNA的存在得以证明。同样的检测方法能够清晰地区分包虫病与由细粒棘球绦虫引起的囊型包虫病。这些数据明确证明波兰存在人体感染多房棘球绦虫的情况。
