Rogala Edmund, Rymarczyk Barbara
Katedra i Klinka Chorób Wewnetrznych, Alergologii i Immunologii Klinicznej Slaskiej Akademii Medycznej w Zabrzu.
Pol Merkur Lekarski. 2003 Jun;14(84):510-3.
The widely understood environmental influence plays an important role in the formation of atopic phenotype. The manifestation of clinical symptoms and signs of asthma is the resultant of the effects of many genes and gene-gene and gene-environment interactions. Based on recent literature data the main environmental factors are analysed, such as tobacco smoke, viral infections, living conditions, moisture and moulds, diet and air pollution. Understanding of these genetic determinants and the role of environmental factors would make possible to improve the methods of diagnosis and treatment.
人们普遍理解环境影响在特应性表型的形成中起着重要作用。哮喘临床症状和体征的表现是许多基因以及基因-基因和基因-环境相互作用的结果。基于近期文献数据，分析了主要的环境因素，如烟草烟雾、病毒感染、生活条件、湿度和霉菌、饮食及空气污染。了解这些遗传决定因素和环境因素的作用将有助于改进诊断和治疗方法。
