Siergiejko Zenon
Klinika Alergologii i Chorób Wewnetrznych Akademii Medycznej w Białymstoku.
Pol Merkur Lekarski. 2003 Jun;14(84):545-7.
Scientific studies of the material obtained during bronchial biopsy, bronchoalveolar lavage and sputum induction altered the view on the pathogenesis of asthma and COPD. In the result, both bronchial diseases are considered inflammatory. Eosinophils play the main role in the pathogenesis of asthma, whereas in COPD the most significant are neutrophils. Bronchial biopsy and bronchoalveolar lavage have been applied mainly in scientific studies, while sputum induction as a non-invasive method can be useful in everyday practice too. Increased level of eosinophils in sputum allows to forecast the efficiency of glucocorticosteroids in the therapy of asthma and COPD.
对支气管活检、支气管肺泡灌洗和痰液诱导所获材料进行的科学研究改变了人们对哮喘和慢性阻塞性肺疾病（COPD）发病机制的看法。结果，这两种支气管疾病都被认为是炎症性疾病。嗜酸性粒细胞在哮喘发病机制中起主要作用，而在COPD中，最重要的是中性粒细胞。支气管活检和支气管肺泡灌洗主要应用于科学研究，而痰液诱导作为一种非侵入性方法在日常实践中也可能有用。痰液中嗜酸性粒细胞水平升高有助于预测糖皮质激素治疗哮喘和COPD的疗效。
