[Skin adverse drug reactions].

Adverse drug reactions are common and important complications of therapy. The clinical picture of drug-induced reactions is characterised by considerable polymorphism: from mild local lesions to fatal systemic processes. The classification of drug hypersensitivity encompasses systemic or specific organ forms. Skin has a special position in the diagnostics of adverse drug-induced reactions. Cutaneous lesions are almost universal and highly pathognomonic symptoms of drug-induced hypersensitivity. Urticaria, erythema-like skin reactions, drug-induced exanthemas, purpuric and hemorrhagic reactions are the most common cutaneous drug-induced manifestations.