Hirabayashi Miki, Ohta Makoto, Rüfenacht Daniel A, Chopard Bastien
CUI, Department d'Informatique, University of Geneva, 24 rue du General-Dufour, CH-1211 Geneva 4, Switzerland.
Phys Rev E Stat Nonlin Soft Matter Phys. 2003 Aug;68(2 Pt 1):021918. doi: 10.1103/PhysRevE.68.021918. Epub 2003 Aug 26.
We consider a lattice Boltzmann simulation of blood flow in a vessel deformed by the presence of an aneurysm. Modern clinical treatments involve introducing a stent (a tubular mesh of wires) into the cerebral artery in order to reduce the flow inside the aneurysm and favor its spontaneous reabsorption. A crucial question is to design the stent with suitable porosity so as to produce the most effective flow reduction. We propose a stent positioning factor as a characterizing tool for stent pore design in order to describe the flow reduction effect and reveal the several flow reduction mechanisms using this effect.
我们考虑对存在动脉瘤而变形的血管中的血液流动进行格子玻尔兹曼模拟。现代临床治疗包括将支架(金属丝制成的管状网)引入脑动脉,以减少动脉瘤内的血流并促进其自发再吸收。一个关键问题是设计具有合适孔隙率的支架,以便最有效地减少血流。我们提出一个支架定位因子作为支架孔隙设计的表征工具,以描述血流减少效果并利用该效果揭示几种血流减少机制。