Ybarra J, de Stefano M, Kammer A, de Tonnac N, Lehmann T, Golay A
Department of Obstetrics and Gynaecology, Dexeus University Institute, Barcelona, Spain.
Diabetes Metab. 2003 Sep;29(4 Pt 1):418-23. doi: 10.1016/s1262-3636(07)70053-8.
The aim of this retrospective study was to identify key factors favoring weight regain.
Therefore, prognostic factors for weight loss and regain have been retrieved and identified among 186 obese patients (40 +/- 2 y and 34 +/- 0.3 kg/m(2)) through the use of a simple questionnaire which considered psychological issues such as depression, anxiety and the patient's individual capacity to follow a diet. All patients have been prescribed a low-calorie diet (1200 kcal/day) being either balanced, food-combining or low-CHO. Follow-up averaged 6.4 +/- 0.3 months of which weight loss accounted for 4.4 +/- 0.1 months.
Weight loss was similar in all 3 groups and averaged 6.0 +/- 0.2 kg. The final weight loss and weight regain results have been identical for the 3 groups. A high/bad prognostic score rating is associated with weight regain (P<0.02). Weight regain is significantly influenced by the initial weight loss speed (P<0.0001).
The proposed prognostic score is likely to be helpful for clinicians better to profile the therapeutic approach to individualized obesity management and follow-up. Diet composition does not influence either weight loss or weight regain.
本回顾性研究旨在确定有利于体重反弹的关键因素。
因此,通过使用一份简单问卷,在186名肥胖患者(40±2岁,体重指数34±0.3kg/m²)中检索并确定了体重减轻和反弹的预后因素,该问卷考虑了诸如抑郁、焦虑等心理问题以及患者遵循饮食的个人能力。所有患者均被规定采用低热量饮食(1200千卡/天),饮食类型为均衡饮食、食物搭配饮食或低碳水化合物饮食。随访平均为6.4±0.3个月,其中体重减轻阶段占4.4±0.1个月。
所有3组的体重减轻情况相似,平均减轻6.0±0.2千克。3组的最终体重减轻和体重反弹结果相同。高/不良预后评分与体重反弹相关(P<0.02)。体重反弹受初始体重减轻速度的显著影响(P<0.0001)。
所提出的预后评分可能有助于临床医生更好地规划个性化肥胖管理和随访的治疗方法。饮食组成对体重减轻或体重反弹均无影响。