Kaden Volker, Renner Christiane, Rothe Anke, Lange Elke, Hänel Andreas, Gossger Klaus
Institut für Infektionsmedizin, Bundesforschungsanstalt für Viruskrankheiten der Tiere, Insel Riems.
Berl Munch Tierarztl Wochenschr. 2003 Sep-Oct;116(9-10):362-7.
The oral immunisation of wild boar against classical swine fever (CSF) in Baden-Württemberg is described and evaluated. The bait vaccine based on the CSF virus (CSFV) strain "C" proved to be safe in wild boar of all age classes. The modified immunisation procedure consisting of three double vaccinations per year was very effective. CSFV was not detected beyond the second immunisation campaign. The average rate of seropositive wild boar diagnosed over all immunisation periods was 49.2%. The seroprevalence rate increased significantly during the first year of immunisation and reached its maximum after the third vaccination period with 72% antibody positive animals. The higher percentage of seropositive young boars in this field trial compared to the seroprevalence rates in this age class in other field trials in Germany may be attributed to the new vaccination scheme. Factors that may be responsible for the decreased herd immunity after the fourth or sixth immunisation period are discussed.
本文描述并评估了在巴登-符腾堡州对野猪进行经典猪瘟(CSF)口服免疫的情况。基于猪瘟病毒(CSFV)“C”株的诱饵疫苗在所有年龄段的野猪中均被证明是安全的。每年进行三次双剂量疫苗接种的改良免疫程序非常有效。在第二次免疫活动之后未检测到猪瘟病毒。在所有免疫期间诊断出的血清阳性野猪的平均比例为49.2%。在免疫的第一年,血清阳性率显著上升,在第三次疫苗接种期后达到最高,抗体阳性动物比例为72%。与德国其他野外试验中该年龄组的血清阳性率相比,本次野外试验中血清阳性的年轻野猪比例更高,这可能归因于新的疫苗接种方案。本文还讨论了在第四次或第六次免疫期后群体免疫力下降可能的影响因素。