Turova T P
Institute of Microbiology, Russian Academy of Sciences, pr. 60-letiya Oktyabrya 7, k. 2, Moscow, 117312 Russia.
Mikrobiologiia. 2003 Jul-Aug;72(4):437-52.
Different aspects of the presence of multiple copies of ribosomal operons in prokaryotic genomes are reviewed. Structure of prokaryotic ribosomal operons is briefly described. The available data are summarized regarding the copy number of ribosomal genes in various prokaryotic genomes, the degree of polymorphism of their individual copies, physiological and evolutionary aspects of the presence of the multiple copies of ribosomal genes. The review also considers the influence of the presence of multiple copies of ribosomal genes on the results of identification of prokaryotic isolates and of the studies of prokaryotic diversity in environmental samples based on phylogenetic analysis of 16S rRNA gene sequences.
本文综述了原核生物基因组中核糖体操纵子多拷贝存在的不同方面。简要描述了原核生物核糖体操纵子的结构。总结了关于各种原核生物基因组中核糖体基因拷贝数、其单个拷贝的多态性程度、核糖体基因多拷贝存在的生理和进化方面的现有数据。该综述还考虑了核糖体基因多拷贝的存在对原核生物分离株鉴定结果以及基于16S rRNA基因序列系统发育分析的环境样品中原核生物多样性研究结果的影响。
