Bentley Janna M, Barankin Benjamin, Lauzon Gilles J
University of Alberta, Edmonton.
Can Fam Physician. 2003 Sep;49:1111-6.
To review the epidemiology, etiology, diagnosis, management, and prognosis of the most common, potentially lethal, lip lesions: leukoplakia, actinic cheilitis, and squamous cell carcinoma (SCC). QUALITY OF EVIDENCE MEDLINE: was searched from 1966 to 2002 for English-language articles on prevalence of lip lesions. No articles for a family physician audience were found. MEDLINE was searched again using the terms "leukoplakia," "actinic cheilitis," and "squamous cell carcinoma." Randomized, controlled trials were selected; non-blinded trials, population-based studies, and systematic reviews were also used.
Leukoplakia, actinic cheilitis, and SCC of the lips are relatively common presentations that can cause substantial morbidity and, more rarely, mortality. Any abnormality of the lips can be an embarrassment. Because of the seriousness and frequency of lip disease, it is important to look for, diagnose, and treat lip lesions to prevent morbidity and mortality and also to maintain social acceptance and self-esteem.
Knowledge of leukoplakia, actinic cheilitis, and SCC of the lips will aid family physicians in diagnosing and managing these lesions and in preventing associated morbidity and mortality.
回顾最常见的、具有潜在致命性的唇部病变:白斑、光化性唇炎和鳞状细胞癌(SCC)的流行病学、病因、诊断、治疗及预后。证据质量 检索1966年至2002年的MEDLINE数据库,查找关于唇部病变患病率的英文文章。未找到面向家庭医生读者的文章。再次使用“白斑”“光化性唇炎”和“鳞状细胞癌”等术语检索MEDLINE数据库。选取随机对照试验;也纳入了非盲法试验、基于人群的研究和系统评价。
唇部白斑、光化性唇炎和鳞状细胞癌是相对常见的表现,可导致严重的发病情况,较少情况下可导致死亡。唇部的任何异常都可能令人尴尬。由于唇部疾病的严重性和发生率,寻找、诊断和治疗唇部病变以预防发病和死亡,并维持社会接纳度和自尊非常重要。
了解唇部白斑、光化性唇炎和鳞状细胞癌将有助于家庭医生诊断和处理这些病变,并预防相关的发病和死亡情况。