Peters W, Irving J, Letts M
Section of Orthopaedics, Winnipeg Children's Hospital, Canada.
J Pediatr Orthop. 1992 Nov-Dec;12(6):806-10. doi: 10.1097/01241398-199211000-00020.
Review of children with physeal damage from neonatal infection other than the hip at Winnipeg Children's Hospital showed that six patients had residual growth interference from adjacent infection in the bone or joint. Several of the infections involved multiple joints, with growth plate arrest occurring in the distal femoral growth plate in four, in the proximal humerus in four, in the proximal femur in two, in the distal radius in one, and in the distal humerus in one. Although the initial infection was frequently believed to be successfully treated in the neonate, the clinical effect of these infections on the growth plate was not fully appreciated in five of the infants until the children reached a mean age of 9 years. Because growth abnormalities in physeal bars may not be clinically evident for several years after the initial infection has been treated, we recommend that children with bone and joint infections occurring in the first month of life be followed to skeletal maturity, observing the adjacent physis for late tethering.
温尼伯儿童医院对除髋关节外因新生儿感染导致骨骺损伤的儿童进行的回顾显示，有6名患者因相邻骨骼或关节感染出现了生长干扰。其中几例感染累及多个关节，生长板停滞发生在股骨远端生长板的有4例，肱骨近端的有4例，股骨近端的有2例，桡骨远端的有1例，肱骨远端的有1例。尽管最初认为新生儿的感染已得到成功治疗，但在其中5名婴儿中，直到儿童平均年龄达到9岁时，这些感染对生长板的临床影响才得到充分认识。由于在最初感染得到治疗后的几年里，骨骺条的生长异常在临床上可能并不明显，我们建议对出生后第一个月内发生骨和关节感染的儿童进行随访至骨骼成熟，观察相邻骨骺是否出现晚期束缚。
