儿童经骨骺血源性骨髓炎的预后：三例报告及文献综述
Prognosis of transphyseal hematogenous osteomyelitis in children: three case reports and a literature review.
作者信息
Ning Peng, Lin Shuting, Yang Zhixin, Liu Tianjing
机构信息
Department of Pediatric Orthopedics, Shengjing Hospital of China Medical University, Shenyang, 110004, China.
, No.36 Sanhao Street, Heping District, Shenyang, Liaoning, China.
出版信息
BMC Musculoskelet Disord. 2025 Mar 11;26(1):237. doi: 10.1186/s12891-025-08475-5.
BACKGROUND
Transphyseal hematogenous osteomyelitis(THO) has been considered a potential cause of severe sequelae due to its damage to the growth plate. It has been reported that growth disturbance would take place if the area of involvement exceeds 7%. However, the growth plate seems to have more potential to recover and regain normal function.
CASE PRESENTATION
We report three cases of hematogenous osteomyelitis(HO) in children (ages 9 weeks, 4 years, and 13 years respectively ) with significant physeal involvement. All patients underwent surgical debridement and antibiotic therapy. Follow-up assessments demonstrated full recovery, with normal knee movements, no pain and equal limb length. Complete recovery of the physeal plate morphology and normal subsequent development were observed.
CONCLUSIONS
THO in children may have the chance of complete recovery after proper treatment, suggesting that the physeal plate has a great potential for self-recovery.
CLINICAL TRIAL NUMBER
Not applicable.
背景
经骨骺血源性骨髓炎（THO）因其对生长板的损害，一直被认为是导致严重后遗症的潜在原因。据报道，如果受累面积超过7%，将会发生生长紊乱。然而，生长板似乎具有更大的恢复潜力并能重新获得正常功能。
病例报告
我们报告3例血源性骨髓炎（HO）患儿（年龄分别为9周、4岁和13岁），其生长板有明显受累。所有患者均接受了外科清创和抗生素治疗。随访评估显示完全恢复，膝关节活动正常，无疼痛，肢体长度相等。观察到生长板形态完全恢复且随后发育正常。
结论
儿童经骨骺血源性骨髓炎经适当治疗后可能有完全恢复的机会，提示生长板具有很大的自我恢复潜力。
临床试验编号
不适用。
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