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实验老年学对临床老年医学的意义(作者译)

[The significance of experimental gerontology for clinical geriatrics (author's transl)].

作者信息

Kment A

出版信息

Aktuelle Gerontol. 1976 Mar;6(3):93-102.

PMID:14528
Abstract

Aging is a physiological process. The experimental gerontology is substantially a purely theoretical science. In the future, however, it will attain increasingly more significance for many fields of medicine. After presenting a survey covering the most important theories of aging it is shortly entered into the efforts to establish a mathematical model of multicellular aging (Beier, Brehme and Wiegel 1973). Furthermore an introduction is given into a longitudinal program (3 years) of the own experimental-gerontological research using about 1000 Sprague-Dawley rats and age parameters. The mathematical evaluation of the results shall contribute to come to more exact and objective statements about age and vitality. The significance of the theoretical-experimental gerontology lies mainly in its efforts to study the fundamental conditions and the possibilities for a longer maintenance of vitality by systematic measures and to reduce or retard the susceptibility to the socalled age-diseases.

摘要

衰老乃一生理过程。实验老年学本质上是一门纯理论科学。然而,未来它在医学诸多领域将愈发重要。在介绍了衰老的最重要理论后,简要阐述了建立多细胞衰老数学模型的努力(拜尔、布雷姆和维格尔,1973年)。此外,还介绍了一项为期三年的自身实验老年学研究纵向计划,该计划使用约1000只斯普拉格-道利大鼠及年龄参数。对结果的数学评估应有助于就年龄与活力得出更精确、客观的结论。理论实验老年学的意义主要在于努力通过系统措施研究维持活力更长久的基本条件及可能性,并降低或延缓对所谓老年疾病的易感性。

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