Khaldoun T, Giry J, Delost P
C R Seances Soc Biol Fil. 1977;171(4):784-90.
Plasma aldosterone concentrations were measured by radioimmunoassay and metabolic clearance rates (M.C.R.) were determined by a continuous infusion of H3-aldosterone on day 20 and 50 and at 3, 6 and 24 months in the male and the female guinea-pig. Plasma aldosterone concentration rose gradually from day 20 up to 24 months. At every stage the values were always higher in the female than in the male. M.C.R. (1/24 h/100 g) decreased from day 20 to 24 months and appeared to be sex-dependent in the guinea-pig.
采用放射免疫分析法测定血浆醛固酮浓度，并通过在雄性和雌性豚鼠的第20天、第50天以及3个月、6个月和24个月时连续输注H3-醛固酮来测定代谢清除率（M.C.R.）。血浆醛固酮浓度从第20天到24个月逐渐升高。在每个阶段，雌性豚鼠的值总是高于雄性。豚鼠的M.C.R.（每24小时每100克）从第20天到24个月降低，且似乎存在性别依赖性。
