Planchard D, Moreau F, Paquereau J, Neau J-P, Meurice J-C
Service de Pneumologie, CHU de Poitiers, 350, avenue Jacques Coeur, Poitiers, France.
Rev Mal Respir. 2003 Sep;20(4):558-65.
Sleep apnoea/hypopnoea syndrome (SAHS) is distinct in the elderly as age-related co-morbidity may be aggravated by sleep-related breathing disorders or may mask typical clinical symptoms.
The SAHS prevalence in the elderly varies from one study to another, with an average rate of 25% that might increase according to the importance of associated pathologies. Clinical symptoms tend to be the neurological manifestations of excessive daytime sleepiness and cognitive deterioration.
Treatment of SAHS should include weight reduction strategies if obesity is present. There is no role for surgery in this age group. On the other hand, adjustable oral appliances can be used depending on the severity of the SAHS, but nasal continuous positive airway pressure (CPAP) remains the most effective therapy available. Acceptance of and compliance with CPAP treatment is as good in this age group as in younger patients, with remarkable effectiveness in terms of improvement in daytime sleepiness and cognitive function. However, the effectiveness of treatment for SAHS is related to the level of symptoms present and this should be taken into account when making a therapeutic decision.
These results fully justify treatment of SAHS in the elderly, but the decision to treat should be governed by the level of clinical symptoms from SAHS.
睡眠呼吸暂停/低通气综合征(SAHS)在老年人中具有特殊性,因为与年龄相关的合并症可能会因睡眠相关呼吸障碍而加重,或者可能掩盖典型的临床症状。
老年人中SAHS的患病率因研究而异,平均患病率为25%,根据相关病理情况的严重程度可能会有所增加。临床症状往往表现为白天过度嗜睡和认知功能恶化等神经学表现。
如果存在肥胖,SAHS的治疗应包括减重策略。在这个年龄组中手术没有作用。另一方面,可根据SAHS的严重程度使用可调节口腔矫治器,但鼻持续气道正压通气(CPAP)仍然是最有效的治疗方法。这个年龄组对CPAP治疗的接受度和依从性与年轻患者一样好,在改善白天嗜睡和认知功能方面效果显著。然而,SAHS治疗的有效性与现有症状水平有关,在做出治疗决策时应考虑到这一点。
这些结果充分证明了对老年人SAHS进行治疗的合理性,但治疗决策应取决于SAHS的临床症状水平。