Leleu O, Clarot C, Renaud H, Brahimi M, Lelarge C, Makdassi R
Service de Pneumologie, Hôpital d'Abbeville, France.
Rev Mal Respir. 2003 Sep;20(4):618-21.
Pulmonary diseases during the course of generalised amyloidosis are principally represented by tracheobronchial involvement and diffuse parenchymal localizations.
The authors report the case of a 66-year-old woman presenting with pleural amyloidosis in the context of generalised amyloidosis. Thoracoscopy performed in the investigation of recurrent transudative pleural effusions found evidence of an inflamed parietal pleura with areas of calcification. Pleural biopsies confirmed amyloid infiltration pleural ossification. Talc pleurodesis was performed.
The authors' conclusion is that, meeting an unexplained pleural effusion even transudative during the course of a generalised amyloidosis, the thoracoscopy is the diagnosis key test as it allows moreover a pleural pleurodesis to be performed.
全身性淀粉样变性病程中的肺部疾病主要表现为气管支气管受累和弥漫性实质病变。
作者报告了一例66岁女性，在全身性淀粉样变性背景下出现胸膜淀粉样变性。在对复发性漏出性胸腔积液进行调查时进行的胸腔镜检查发现壁层胸膜有炎症且有钙化区域。胸膜活检证实有淀粉样浸润和胸膜骨化。进行了滑石粉胸膜固定术。
作者的结论是，在全身性淀粉样变性病程中遇到不明原因的胸腔积液（即使是漏出性）时，胸腔镜检查是诊断的关键检查，因为它还允许进行胸膜固定术。
