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酷似胸膜恶性肿瘤的胸膜淀粉样变性

Pleural amyloidosis imitating pleural malignancy.

作者信息

Coolbear Frith, Bilawich Ana-Maria, Tongson Jonathan, Adamo James, Churg Andrew

机构信息

Department of Radiology, Vancouver General Hospital and University of British Columbia, Vancouver, BC, Canada.

Preferred Associates of Pathology, Genesis HealthCare, Zanesville, OH, USA.

出版信息

Respir Med Case Rep. 2017 Mar 6;20:195-197. doi: 10.1016/j.rmcr.2017.03.004. eCollection 2017.

DOI:10.1016/j.rmcr.2017.03.004
PMID:28331795
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5345968/
Abstract

CT chest performed to investigate dyspnea and malaise in an 83 year old man demonstrated bilateral circumferential pleural thickening highly suspicious for pleural mesothelioma or metastatic pleural malignancy. Histopathology of a subsequent pleural biopsy returned a diagnosis of pleural amyloid. This case identifies pleural amyloid as a rare differential consideration for diffuse pleural thickening; the difficulties in distinguishing pleural amyloid from pleural malignancy are highlighted.

摘要

对一名83岁男性因呼吸困难和全身不适进行的胸部CT检查显示双侧环形胸膜增厚,高度怀疑为胸膜间皮瘤或转移性胸膜恶性肿瘤。随后胸膜活检的组织病理学检查结果为胸膜淀粉样变。该病例表明胸膜淀粉样变是弥漫性胸膜增厚的一种罕见鉴别诊断;强调了区分胸膜淀粉样变与胸膜恶性肿瘤的困难。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78a8/5345968/2fcc8455e66d/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78a8/5345968/881de60d2bc6/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78a8/5345968/9780259c297c/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78a8/5345968/2fcc8455e66d/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78a8/5345968/881de60d2bc6/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78a8/5345968/9780259c297c/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78a8/5345968/2fcc8455e66d/gr3.jpg

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本文引用的文献

1
Amyloidosis of the Lung.肺淀粉样变性
Arch Pathol Lab Med. 2017 Feb;141(2):247-254. doi: 10.5858/arpa.2016-0102-RA.
2
Asymptomatic localized pleural amyloidosis mimicking malignant pleural mesothelioma: report of a case.无症状局限性胸膜淀粉样变误诊为恶性胸膜间皮瘤:一例报告
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Recurrent Pleural Effusions Occurring in Association with Primary Pulmonary Amyloidosis.与原发性肺淀粉样变性相关的复发性胸腔积液
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Pleural amyloidosis mimicking mesothelioma: a clinicopathologic study of two cases.
Ann Diagn Pathol. 2001 Aug;5(4):229-32. doi: 10.1053/adpa.2001.27257.
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Eur Respir J. 1989 Apr;2(4):366-9.