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使用大口径金属支架封闭食管创伤性非恶性穿孔。

Use of large-diameter metallic stents to seal traumatic nonmalignant perforations of the esophagus.

作者信息

Siersema Peter D, Homs Marjolein Y V, Haringsma Jelle, Tilanus Huug W, Kuipers Ernst J

机构信息

Department of Gastroenterology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands.

出版信息

Gastrointest Endosc. 2003 Sep;58(3):356-61. doi: 10.1067/s0016-5107(03)00008-7.

Abstract

BACKGROUND

Surgery for traumatic, non-malignant perforation of the esophagus in patients presenting more than 24 hours after its occurrence carries a high morbidity and mortality. Covered metallic stents have been used to effectively seal perforations in individual patients with Boerhaave's syndrome.

METHODS

Eleven consecutive patients presented with esophageal perforation that was caused by Boerhaave's syndrome (n = 5), resection of an epiphrenic diverticulum (n = 2), rigid esophagoscopy (n = 2), extended gastric resection (n = 1), or pneumatic dilation for achalasia (n = 1). A large diameter Flamingo Wallstent (proximal/distal diameters, 30/20 mm) (7 patients) or a large diameter Ultraflex stent (proximal/distal diameters, 28/23 mm) (4 patients) was placed. Pleural cavities were drained with thoracostomy drains, and antibiotics were administered.

RESULTS

The median time from perforation to stent insertion was 60 hours (range, 24 hours to 28 days). The perforation was totally sealed in 10 of 11 patients. Two patients underwent esophageal resection because of incomplete sealing of the perforation or incomplete drainage of the pleural cavity and mediastinum. The other 9 patients recovered uneventfully and resumed a normal diet within 7 to 18 days. In 7 patients, the stents were retrieved endoscopically after a median of 7 weeks (range, 6 to 14 weeks), whereas two patients refused to have the stent retrieved (in one, the stent migrated into the stomach; the other patient died 6 months after stent placement from an unrelated cause).

CONCLUSIONS

Traumatic perforation of the esophagus can be treated successfully with large diameter metallic stents, together with adequate drainage of the thoracic cavity.

摘要

背景

食管发生创伤性、非恶性穿孔后超过24小时就诊的患者,手术治疗的发病率和死亡率很高。覆膜金属支架已被用于有效封闭患有博赫哈夫综合征的个别患者的穿孔。

方法

连续11例患者出现食管穿孔,病因分别为博赫哈夫综合征(5例)、膈上憩室切除术(2例)、硬质食管镜检查(2例)、扩大胃切除术(1例)或贲门失弛缓症的气囊扩张术(1例)。放置了大直径的火烈鸟Wallstent支架(近端/远端直径,30/20毫米)(7例患者)或大直径的Ultraflex支架(近端/远端直径,28/23毫米)(4例患者)。通过胸腔闭式引流管引流胸腔,并给予抗生素治疗。

结果

从穿孔到支架置入的中位时间为60小时(范围为24小时至28天)。11例患者中有10例穿孔完全封闭。2例患者因穿孔封闭不完全或胸腔及纵隔引流不完全而接受了食管切除术。其他9例患者恢复顺利,在7至18天内恢复正常饮食。7例患者在中位时间为7周(范围为6至14周)后通过内镜取出支架,而2例患者拒绝取出支架(1例中,支架移入胃内;另1例患者在支架置入6个月后因无关原因死亡)。

结论

食管创伤性穿孔可通过大直径金属支架成功治疗,并同时充分引流胸腔。

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