Monge-Rojas Rafael, Alfaro Calvo Thelma, Nuñez Rivas Hilda
Costa Rican Institute for Research and Education on Nutrition and Health (INCIENSA), Tres Ríos, Costa Rica.
Arch Latinoam Nutr. 2003 Jun;53(2):165-71.
Results from several studies have suggested that vitamin E intake could inhibit the progression of atherosclerotic lesions. Therefore, this study was designed to evaluate Costa Rican adolescents' serum alpha-tocopherol levels and their correlation with Body Mass Index (BMI) and the dietary intake of vitamin E and saturated and polyunsaturated fat. Ninety-five healthy, non-smoking adolescents and non-vitamin supplement users (aged 13-18) from urban and rural areas in San José, Costa Rica, were included in this study. Serum levels of lipid adjusted alpha-tocopherol were significantly higher in rural adolescents compared with urban youngsters (4.192 mumol/mmol +/- 0.831 and 3.486 mumol/mmol +/- 0.996, respectively). Likewise, reported mean daily 1000 kcal adjusted-vitamin E intake was higher in rural adolescents than in urban youngsters (9.2 +/- 3.7 mg. 16.0 +/- 8.7 mg). An important correlation was observed between intake of energy from saturated fat and adjusted-alpha-tocopherol serum levels (r = 0.430). Contrariwise, they correlated poorly with dietary alpha-tocopherol (r = 0.273), suggesting that serum is not a good biomarket of intake for alpha-tocopherol. Additionally, our results showed a negative relationship between BMI and adjusted-serum vitamin E levels (beta = 0.189; CI 95% -0.153, -0.013). The analysis of vitamin E intake showed that over 25% of adolescents have inadequate intake of the nutrient. This study suggests that nutritionists and pediatricians should encourage alpha-tocopherol intake and monitor the food sources of the nutrient and the adolescents' body weight as part of the strategies aimed at developing a healthy lifestyle.
多项研究结果表明，摄入维生素E可能会抑制动脉粥样硬化病变的发展。因此，本研究旨在评估哥斯达黎加青少年的血清α-生育酚水平，以及它们与体重指数（BMI）、维生素E饮食摄入量、饱和脂肪和多不饱和脂肪摄入量之间的相关性。本研究纳入了95名来自哥斯达黎加圣何塞城乡地区的健康、不吸烟且不使用维生素补充剂的青少年（年龄在13 - 18岁）。农村青少年经脂质调整后的血清α-生育酚水平显著高于城市青少年（分别为4.192 μmol/mmol ± 0.831和3.486 μmol/mmol ± 0.996）。同样，据报告，农村青少年经1000千卡调整后的每日维生素E摄入量高于城市青少年（9.2 ± 3.7毫克对16.0 ± 8.7毫克）。观察到饱和脂肪能量摄入量与经调整的α-生育酚血清水平之间存在重要相关性（r = 0.430）。相反，它们与饮食中的α-生育酚相关性较差（r = 0.273），这表明血清并非α-生育酚摄入量的良好生物标志物。此外，我们的结果显示BMI与经调整的血清维生素E水平之间存在负相关关系（β = 0.189；95%置信区间为 -0.153，-0.013）。对维生素E摄入量的分析表明，超过25%的青少年该营养素摄入不足。本研究表明，营养学家和儿科医生应鼓励青少年摄入α-生育酚，并监测该营养素的食物来源以及青少年的体重，以此作为培养健康生活方式策略的一部分。
