Shan Limei, Zhao Yanlin, Xiao Xiaohe, Cai Guangming, He Chengshan
302 Hospital of PLA, Beijing 100039.
Zhong Yao Cai. 2003 Jun;26(6):420-2.
The anthraco-propulsion and the drug induced mice diarrhea models were used to observe the intestine propulsion and the anti-diarrhea effect of "Tao Hua Zhi Xie Granule" (THZXG), and the anti-inflammation effect of THZXG was studied. The results showed that THZXG could obviously reduce the incidence and frequency of the mice diarrhea induced by Folium Sennae and castor-oil, and propelling movement of mice small intestine after hypodermic injection of neostigmine. The actions were acted in a dose-dependent manner. 11.70 and 17.55 mg/kg THZXG(ig) could also inhibit the increased permeability of intraperitoneal capillary induced by acetic acid in mice.
采用炭末推进法和药物致小鼠腹泻模型，观察“桃花止泻颗粒”（THZXG）对肠道推进及止泻作用，并研究其抗炎作用。结果显示，THZXG能明显降低番泻叶和蓖麻油所致小鼠腹泻的发生率和次数，以及皮下注射新斯的明后小鼠小肠的推进运动。其作用呈剂量依赖性。11.70和17.55mg/kg THZXG（灌胃）还能抑制醋酸所致小鼠腹腔毛细血管通透性增高。
