White L C, Buchanan K D, O'Leary T D, Carlan S J, Boothby R
Department of Obstetrics/Gynecology, Arnold Palmer Hospital, Orlando Regional Healthcare System, Orlando, FL 32806, USA.
Gynecol Oncol. 2003 Oct;91(1):254-7. doi: 10.1016/s0090-8258(03)00405-0.
Sertoli-Leydig cell tumors (SLCT) constitute only 0.5% of all primary ovarian neoplasms. We report a unique diagnostic method (selective laparoscopic venous sampling) and a rare case of a contralateral second primary tumor.
A 14-year-old female presented with hyperandrogenic complaints and an increased serum testosterone. Ovarian origin was confirmed by direct laparoscopic ovarian blood sampling. A right salpingo-oophorectomy was performed. The pathological diagnosis was SLCT of intermediate differentiation. Three years later, the patient presented again with an increased serum testosterone. A solid tumor in the left ovary was excised. The pathology was SLCT of intermediate differentiation. The patient remains disease-free.
Direct laparoscopic venous sampling is used to diagnose a small SLCT in a teenage patient.
支持-间质细胞瘤（SLCT）仅占所有原发性卵巢肿瘤的0.5%。我们报告一种独特的诊断方法（选择性腹腔镜静脉采血）以及一例罕见的对侧第二原发性肿瘤病例。
一名14岁女性因高雄激素症状及血清睾酮升高就诊。通过直接腹腔镜卵巢采血确诊为卵巢来源。行右侧输卵管卵巢切除术。病理诊断为中等分化的支持-间质细胞瘤。三年后，患者血清睾酮再次升高。切除左侧卵巢的实性肿瘤。病理为中等分化的支持-间质细胞瘤。患者目前无疾病复发。
直接腹腔镜静脉采血用于诊断青少年患者的小支持-间质细胞瘤。
