Lantzsch T, Stoerer S, Lawrenz K, Buchmann J, Strauss H G, Koelbl H
Department of Gynecology, Martin-Luther-University, Halle-Wittenberg, Halle/Saale, Germany.
Arch Gynecol Obstet. 2001 Jan;264(4):206-8. doi: 10.1007/s004040000114.
Sertoli-Leydig cell tumors belong to the group of sex-cord stromal tumors of the ovary. They account for less than 0,5% of all ovarian neoplasms. The majority of these tumors are benign, and almost all are localised unilaterally. Herewith, we describe an ovarian Sertoli-Leydig cell tumor in an 11-year-old girl. Serum levels of estradiol and progesterone were mildly elevated. while testosterone and androstendion levels were raised to around three- and sevenfold upper normal limit respectively on presentation. A left salpingo-oophorectomy was performed. Microscopically, the tumor was intermediately differentiated. At 6 months follow-up, there was neither clinical nor sonographical evidence of recurrence, and almost all sex hormone levels had returned to within normal range. Treatment of this pathological entity has to be individualized according to patient age, stage of tumor and degree of differentiation.
支持-间质细胞瘤属于卵巢性索间质肿瘤。它们占所有卵巢肿瘤的比例不到0.5%。这些肿瘤大多数是良性的，几乎所有肿瘤都单侧局限。在此，我们描述一名11岁女孩的卵巢支持-间质细胞瘤。血清雌二醇和孕酮水平轻度升高，而睾酮和雄烯二酮水平在初诊时分别升高至正常上限的约三倍和七倍。进行了左侧输卵管卵巢切除术。显微镜下，肿瘤为中度分化。随访6个月时，既无临床证据也无超声证据显示复发，几乎所有性激素水平已恢复至正常范围。这种病理实体的治疗必须根据患者年龄、肿瘤分期和分化程度个体化。
