择期与紧急适应证肝移植结果的比较。
Comparison of the results of liver transplantation for elective versus urgent indications.
作者信息
Zieniewicz K, Skwarek A, Nyckowski P, Pawlak J, Michałowicz B, Patkowski W, Najnigier B, Alsharabi A, Hevelke P, Remiszewski P, Smoter P, Dudek K, Grodzicki M, Paczkowska A, Oldakowska-Jedynak U, Niewczas M, Paczek L, Krawczyk M
机构信息
Department of General, Transplantation and Liver Surgery, Medical University of Warsaw, Warsaw, Poland.
出版信息
Transplant Proc. 2003 Sep;35(6):2262-4. doi: 10.1016/s0041-1345(03)00812-1.
The authors present an analysis of early and remote liver transplantation outcomes related to the presence of emergent indications among 196 of the 209 operations performed from 1989 to April 2003; namely 178 elective and 18 emergent transplantations. Perioperative mortality was 15%. The survival rate during the first 12 months was 79.8% and within 3 years 73.5% among patients operated on an elective basis (UNOS 3 and 2B). In contrast, patients with acute liver failure (UNOS 1 and 2A) showed rates of 45%, 50%, and 47%, respectively. Liver transplant outcomes depend primarily on the urgency of an operation. Longterm results are much better among patients operated on electively. Liver transplantation in patients with acute hepatic insufficiency is burdened with a high 45% mortality.
作者对1989年至2003年4月间进行的209例手术中的196例（即178例择期移植和18例急诊移植）与急诊指征相关的早期和远期肝移植结果进行了分析。围手术期死亡率为15%。择期手术患者（美国器官共享联合网络3级和2B级）术后12个月生存率为79.8%，3年内生存率为73.5%。相比之下，急性肝衰竭患者（美国器官共享联合网络1级和2A级）的生存率分别为45%、50%和47%。肝移植结果主要取决于手术的紧迫性。择期手术患者的长期结果要好得多。急性肝功能不全患者的肝移植死亡率高达45%。
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