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[一种使用脉冲多普勒超声的胎儿呼吸运动跟踪系统的开发]

[Development of a fetal breathing movement tracking system using pulsed Doppler ultrasound].

作者信息

Shinozuka N, Yamakoshi Y, Okai T, Mizuno M

机构信息

Department of Obstetrics and Gynecology, Faculty of Medicine, University of Tokyo.

出版信息

Nihon Sanka Fujinka Gakkai Zasshi. 1992 Sep;44(9):1157-64.

PMID:1453045
Abstract

Fetal breathing movements (FBM) form a useful means of monitoring fetal conditions and functional development. To develop a continuous and quantitative FBM monitoring system for clinical use, a non-imaging method using pulsed Doppler was devised. A pulsed Doppler cardiotocograph module was extended to obtain low frequency Doppler signals, by the addition of a 90 degree phase shifter, analog multipliers, quadrature detector, sample and hold circuits and low pass filters, to produce five simultaneous outputs representing movement at depths separated by 1.5cm intervals. These outputs represent the displacement inside tissue at the various depths. Signal processing was executed on a 32-bit computer with an A/D converter. On-line processing by means of a zero-crossing method and off-line arc tangent method with high accuracy displacement estimation were applied for calculation. With this system, FBM was detected as cyclic and regular displacements of a few hundred microns ranging from 0.5 to 1.5Hz. With digital signal processing of 2/3Hz high pass filtering, precise evaluation FBM was possible while rejecting gross movements due to maternal breathing, etc. Although further studies are required for clinical application, it appears that quantitative assessments of FBM should be possible with this technique.

摘要

胎儿呼吸运动(FBM)是监测胎儿状况和功能发育的一种有用手段。为开发一种用于临床的连续定量FBM监测系统,设计了一种使用脉冲多普勒的非成像方法。通过添加90度移相器、模拟乘法器、正交检测器、采样保持电路和低通滤波器,扩展了脉冲多普勒胎心监护仪模块以获取低频多普勒信号,从而产生五个同时输出,代表间隔1.5厘米深度处的运动。这些输出表示不同深度处组织内部的位移。信号处理在带有A/D转换器的32位计算机上执行。通过过零法进行在线处理,并采用具有高精度位移估计的离线反正切法进行计算。使用该系统,FBM被检测为0.5至1.5Hz范围内几百微米的周期性和规则位移。通过2/3Hz高通滤波的数字信号处理,可以在排除母体呼吸等引起的大幅度运动的同时,对FBM进行精确评估。尽管临床应用还需要进一步研究,但看来使用该技术应该能够对FBM进行定量评估。

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