Kostoglou-Athanassiou I, Pappas A, Gogou L, Kaldrymides P
Department of Endocrinology, Metaxa Hospital, Piraeus, Greece.
Horm Res. 2003;60(4):205-8. doi: 10.1159/000073234.
To describe the visualization of recurrent disease by [111In]octreotide and 201Tl scintigraphy in a patient with Hürthle cell thyroid carcinoma, increased thyroglobulin levels, and a negative radio-iodine total-body scan.
Scintigraphy with [111In]octreotide and 201Tl was performed, and a local recurrence in the thyroid bed was detected which was excised by surgery.
On histology, the tumour proved to be a Hürthle cell carcinoma, and within the tumour somatostatin receptors were detected by RT-PCR.
Scintigraphy with [111In]octreotide and 201Tl is an alternative imaging method for the detection of residual disease in patients with a differentiated thyroid carcinoma having increased thyroglobulin levels and a negative radio-iodine total-body scan.
描述在一名患有许特莱细胞甲状腺癌、甲状腺球蛋白水平升高且放射性碘全身扫描阴性的患者中,使用[111In]奥曲肽和201Tl闪烁扫描法对复发性疾病的可视化情况。
进行了[111In]奥曲肽和201Tl闪烁扫描,检测到甲状腺床局部复发,随后通过手术切除。
组织学检查显示,肿瘤为许特莱细胞癌,通过逆转录聚合酶链反应在肿瘤内检测到生长抑素受体。
对于分化型甲状腺癌患者,若甲状腺球蛋白水平升高且放射性碘全身扫描阴性,[111In]奥曲肽和201Tl闪烁扫描是检测残留疾病的一种替代成像方法。