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[111In]奥曲肽和201Tl闪烁扫描法在一例无可检测到的放射性碘摄取的许特耳细胞甲状腺癌中的应用。病例报告及文献复习。

Scintigraphy with [111In]octreotide and 201Tl in a Hürthle cell thyroid carcinoma without detectable radio-iodine uptake. Report of a case and review of the literature.

作者信息

Kostoglou-Athanassiou I, Pappas A, Gogou L, Kaldrymides P

机构信息

Department of Endocrinology, Metaxa Hospital, Piraeus, Greece.

出版信息

Horm Res. 2003;60(4):205-8. doi: 10.1159/000073234.

DOI:10.1159/000073234
PMID:14530610
Abstract

AIM

To describe the visualization of recurrent disease by [111In]octreotide and 201Tl scintigraphy in a patient with Hürthle cell thyroid carcinoma, increased thyroglobulin levels, and a negative radio-iodine total-body scan.

METHODS

Scintigraphy with [111In]octreotide and 201Tl was performed, and a local recurrence in the thyroid bed was detected which was excised by surgery.

RESULTS

On histology, the tumour proved to be a Hürthle cell carcinoma, and within the tumour somatostatin receptors were detected by RT-PCR.

CONCLUSION

Scintigraphy with [111In]octreotide and 201Tl is an alternative imaging method for the detection of residual disease in patients with a differentiated thyroid carcinoma having increased thyroglobulin levels and a negative radio-iodine total-body scan.

摘要

目的

描述在一名患有许特莱细胞甲状腺癌、甲状腺球蛋白水平升高且放射性碘全身扫描阴性的患者中,使用[111In]奥曲肽和201Tl闪烁扫描法对复发性疾病的可视化情况。

方法

进行了[111In]奥曲肽和201Tl闪烁扫描,检测到甲状腺床局部复发,随后通过手术切除。

结果

组织学检查显示,肿瘤为许特莱细胞癌,通过逆转录聚合酶链反应在肿瘤内检测到生长抑素受体。

结论

对于分化型甲状腺癌患者,若甲状腺球蛋白水平升高且放射性碘全身扫描阴性,[111In]奥曲肽和201Tl闪烁扫描是检测残留疾病的一种替代成像方法。

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