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Do vertical shifts in dose-response rate-relationships in operant conditioning procedures indicate "sensitization" to "drug wanting"?

作者信息

Zernig Gerald, Wakonigg Gudrun, Madlung Ekkehard, Haring Christian, Saria Alois

出版信息

Psychopharmacology (Berl). 2004 Jan;171(3):349-51; author reply 352-63. doi: 10.1007/s00213-003-1601-0. Epub 2003 Oct 3.

DOI:10.1007/s00213-003-1601-0
PMID:14530895
Abstract
摘要

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Do vertical shifts in dose-response rate-relationships in operant conditioning procedures indicate "sensitization" to "drug wanting"?操作性条件反射程序中剂量-反应率关系的垂直变化是否表明对“药物渴望”的“敏感化”？
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Psychopharmacology (Berl). 2003 Aug;169(1):52-9. doi: 10.1007/s00213-003-1488-9. Epub 2003 May 21.
2
Effects of chronic d-amphetamine treatment on cocaine- and food-maintained responding under a second-order schedule in rhesus monkeys.慢性右旋苯丙胺治疗对恒河猴在二级强化程序下可卡因及食物维持反应的影响。
Drug Alcohol Depend. 2003 May 1;70(1):39-52. doi: 10.1016/s0376-8716(02)00339-3.
3
The effects of chronic morphine on behavior reinforced by several opioids or by cocaine in rhesus monkeys.
大鼠中可卡因单位剂量反应函数的上升支作为一种实验假象。
Sci Rep. 2023 Oct 3;13(1):16614. doi: 10.1038/s41598-023-43506-y.
4
The activity-regulated cytoskeleton-associated protein, Arc/Arg3.1, influences mouse cocaine self-administration.活性调节细胞骨架相关蛋白 Arc/Arg3.1 影响小鼠可卡因自我给药。
Pharmacol Biochem Behav. 2020 Jan;188:172818. doi: 10.1016/j.pbb.2019.172818. Epub 2019 Nov 1.
5
Making the Case for 'Power Abuse Disorder' as a Nosologic Entity.论证“权力滥用障碍”作为一种疾病分类实体的合理性。
Pharmacology. 2017;100(1-2):50-63. doi: 10.1159/000475600. Epub 2017 May 4.
6
Evaluation of the "Pipeline" for Development of Medications for Cocaine Use Disorder: A Review of Translational Preclinical, Human Laboratory, and Clinical Trial Research.可卡因使用障碍药物研发“管道”评估：转化临床前、人体实验室及临床试验研究综述
Pharmacol Rev. 2016 Jul;68(3):533-62. doi: 10.1124/pr.115.011668.
7
The effects of amphetamine, butorphanol, and their combination on cocaine self-administration.苯丙胺、布托啡诺及其组合对可卡因自我给药的影响。
Behav Brain Res. 2014 Nov 1;274:158-63. doi: 10.1016/j.bbr.2014.08.012. Epub 2014 Aug 12.
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Effects of repeated exposure to morphine in adolescent and adult male C57BL/6J mice: age-dependent differences in locomotor stimulation, sensitization, and body weight loss.青春期和成年雄性C57BL/6J小鼠反复接触吗啡的影响：运动刺激、敏化和体重减轻方面的年龄依赖性差异。
Psychopharmacology (Berl). 2014 Apr;231(8):1517-29. doi: 10.1007/s00213-013-3298-z. Epub 2013 Oct 6.
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Environmental modulation of drug taking: Nonhuman primate models of cocaine abuse and PET neuroimaging.环境对药物滥用的影响：可卡因滥用的非人灵长类动物模型和 PET 神经影像学。
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慢性吗啡对恒河猴中由几种阿片类药物或可卡因强化的行为的影响。
Drug Alcohol Depend. 2001 May 1;62(3):181-9. doi: 10.1016/s0376-8716(00)00166-6.
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Incentive-sensitization and addiction.动机致敏与成瘾
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Drug addiction, dysregulation of reward, and allostasis.药物成瘾、奖赏失调与适应性稳态
Neuropsychopharmacology. 2001 Feb;24(2):97-129. doi: 10.1016/S0893-133X(00)00195-0.
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Cocaine self-administration increases the incentive motivational properties of the drug in rats.可卡因自我给药增强了该药物对大鼠的激励动机特性。
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8
Transition from moderate to excessive drug intake: change in hedonic set point.从适度药物摄入到过度药物摄入的转变：享乐设定点的变化。
Science. 1998 Oct 9;282(5387):298-300. doi: 10.1126/science.282.5387.298.
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The neural basis of drug craving: an incentive-sensitization theory of addiction.药物成瘾渴望的神经基础：一种成瘾的激励敏感化理论
Brain Res Brain Res Rev. 1993 Sep-Dec;18(3):247-91. doi: 10.1016/0165-0173(93)90013-p.
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Tolerance to self-administration of cocaine in rats: time course and dose-response determination using a multi-dose method.
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