肺吸虫病的啮齿动物模型。
A rodent model for pulmonary paragonimiasis.
作者信息
Narain Kanwar, Rekha Devi K, Mahanta J
机构信息
Regional Medical Research Centre, N.E. Region, Indian Council of Medical Research, P.O.B. 105, Dibrugarh 786 001, Assam, India.
出版信息
Parasitol Res. 2003 Dec;91(6):517-9. doi: 10.1007/s00436-003-0973-8. Epub 2003 Oct 7.
This study reports a model of pulmonary paragonimiasis in outbred Wistar rats using the Indian strain of Paragonimus heterotremus isolated from the fresh water crab Barytelphusa lugubris collected from Arunachal Pradesh, India. Feeding metacercariae to the rats led to encapsulated adult worms in the lungs and pleural cavity. Some flukes migrated to the skeletal muscles of the hosts where they remained underdeveloped as immature flukes.
本研究报告了一种在远交系Wistar大鼠中建立肺吸虫病模型的方法，所用的印度异盘并殖吸虫菌株分离自从印度阿鲁纳恰尔邦采集的淡水蟹Barytelphusa lugubris。给大鼠喂食尾蚴后，在肺和胸腔中出现了被包裹的成虫。一些吸虫迁移到宿主的骨骼肌中，在那里它们作为未成熟吸虫保持发育不全的状态。
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