Morimatsu Yoshitaka, Kinoshita Masaharu, Koga Takeharu, Aizawa Hisamichi
First Department of Internal Medicine, Kurume University School of Medicine 67, Asahi-machi, Kurume-city, Fukuoka, Japan.
Nihon Kokyuki Gakkai Zasshi. 2003 Sep;41(9):655-9.
We present a case of allergic rhinitis in a 68-year-old woman in whom eosinophilia was found when she complained of common cold-like symptoms. The patient noticed a mass lesion on her left neck, which improved with antibiotic treatment, but her coughing continued and edema of both lower extremities appeared. She was admitted to our hospital, because of abnormalities in her electrocardiogram and cardiomegaly seen in a chest radiograph. The discomfort due to the edema in the soles of both feet remained even after steroid therapy. Her chest radiograph revealed ground-glass opacity, and a transbronchial lung biopsy revealed granulation tissue with the infiltration of eosinophils into the interstitium. Allergic granulomatosis angiitis was diagnosed because of granulomatosis vasculitis resulting from sural nerve biopsy. This was a rare case of allergic granulomatosis angiitis because her lung function was normal, she had no history of bronchial asthma, and there were no clear symptoms of bronchial asthma.
我们报告一例68岁女性变应性鼻炎病例，该患者主诉有类似普通感冒的症状时被发现嗜酸性粒细胞增多。患者发现左颈部有一肿块，经抗生素治疗后有所改善，但咳嗽持续存在，且出现双下肢水肿。因心电图异常及胸部X线片显示心脏扩大，她入住我院。即使在接受类固醇治疗后，双足底水肿引起的不适仍持续存在。她的胸部X线片显示磨玻璃样混浊，经支气管肺活检显示肉芽组织，嗜酸性粒细胞浸润至间质。因腓肠神经活检导致肉芽肿性血管炎，诊断为变应性肉芽肿性血管炎。这是一例罕见的变应性肉芽肿性血管炎病例，因为她的肺功能正常，无支气管哮喘病史，也没有明确的支气管哮喘症状。
