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无哮喘及血液嗜酸性粒细胞增多的变应性肉芽肿病和血管炎:局限型变应性肉芽肿性血管炎的罕见表现

Allergic granulomatosis and angiitis in the absence of asthma and blood eosinophilia: a rare presentation of limited Churg-Strauss syndrome.

作者信息

Sevinc Alper, Hasanoglu H Canan, Gokirmak Munire, Yildirim Zeki, Baysal Tamer, Mizrak Bulent

机构信息

Department of Internal Medicine, Gaziantep University School of Medicine, Sahinbey Medical Center, Gaziantep 27310, Turkey.

出版信息

Rheumatol Int. 2004 Sep;24(5):301-4. doi: 10.1007/s00296-003-0412-2. Epub 2003 Nov 20.

DOI:10.1007/s00296-003-0412-2
PMID:14628152
Abstract

Allergic granulomatosis and angiitis, also known as Churg-Strauss syndrome (CSS), is an uncommon vasculitis of unknown etiology. We report a 21-year-old male patient with fatigue, dry cough, and progressive dyspnea. He had no history of asthma or eosinophilia. Thorax computed tomography showed bullous/cystic areas with thin walls in varying sizes (5-15 mm). Histopathological examination of the open lung biopsy revealed granulomatous infiltration with histiocytes and eosinophilic leukocytes. This extremely rare variant of CSS is discussed.

摘要

变应性肉芽肿性血管炎,又称Churg-Strauss综合征(CSS),是一种病因不明的罕见血管炎。我们报告一名21岁男性患者,有疲劳、干咳和进行性呼吸困难症状。他无哮喘或嗜酸性粒细胞增多病史。胸部计算机断层扫描显示有大小不一(5 - 15毫米)的薄壁大疱/囊肿区域。开胸肺活检的组织病理学检查显示有组织细胞和嗜酸性白细胞的肉芽肿浸润。本文对CSS这种极其罕见的变异型进行了讨论。

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