Yamashita K, Nohara Y, Katayama K, Namiki M
Department of Food and Nutrition, School of Life Studies, Sugiyama Jogakuen University, Nagoya, Japan.
J Nutr. 1992 Dec;122(12):2440-6. doi: 10.1093/jn/122.12.2440.
Vitamin E activity of sesame seed, which contains only gamma-tocopherol, a compound that has vitamin E activity equal to only 6-16% that of alpha-tocopherol, was examined in two experiments. In the first experiment, groups of rats were fed four diets: vitamin E-free control diet, alpha-tocopherol-containing diet, gamma-tocopherol-containing diet and sesame seed-containing diet. Changes in red blood cell hemolysis, plasma pyruvate kinase activity, and peroxides in plasma and liver, as indices of vitamin E activity, were examined. The sesame seed diet has high vitamin E activity, whereas this activity was low in the gamma-tocopherol diet. In plasma and liver, alpha-tocopherol was found in high concentration only in the alpha-tocopherol-fed group, and gamma-tocopherol was found in high concentration only in the sesame seed-fed group, with negligible amounts of gamma-tocopherol in liver of the gamma-tocopherol-fed group. In the second experiment, two diets containing sesame lignan (sesaminol or sesamin) and gamma-tocopherol were tested. Results in both of the sesame lignan-fed groups were comparable to those observed in the sesame seed-fed group in Experiment 1. These experiments indicate that gamma-tocopherol in sesame seed exerts vitamin E activity equal to that of alpha-tocopherol through a synergistic interaction with sesame seed lignans.
芝麻油仅含有γ-生育酚，该化合物的维生素E活性仅为α-生育酚的6%-16%。在两项实验中对芝麻油的维生素E活性进行了检测。在第一个实验中，给几组大鼠喂食四种日粮：不含维生素E的对照日粮、含α-生育酚的日粮、含γ-生育酚的日粮和含芝麻的日粮。检测红细胞溶血、血浆丙酮酸激酶活性以及血浆和肝脏中的过氧化物的变化，以此作为维生素E活性的指标。含芝麻的日粮具有较高的维生素E活性，而含γ-生育酚的日粮中该活性较低。在血浆和肝脏中，仅在喂食α-生育酚的组中发现高浓度的α-生育酚，仅在喂食芝麻的组中发现高浓度的γ-生育酚，而在喂食γ-生育酚的组的肝脏中γ-生育酚含量可忽略不计。在第二个实验中，测试了两种含有芝麻木脂素（芝麻酚林或芝麻素）和γ-生育酚的日粮。两个喂食芝麻木脂素的组的结果与实验1中喂食芝麻的组所观察到的结果相当。这些实验表明，芝麻中的γ-生育酚通过与芝麻木脂素的协同相互作用发挥与α-生育酚相当的维生素E活性。
