Kamal-Eldin A, Pettersson D, Appelqvist L A
Department of Food Science, Swedish University of Agricultural Sciences, Uppsala.
Lipids. 1995 Jun;30(6):499-505. doi: 10.1007/BF02537023.
Six groups of rats were fed diets low, but adequate, in alpha-tocopherol but high in gamma-tocopherol. The six diets differed only in their contents (0, 0.25, 0.5, 1.0, 2.0, and 4.0 g/kg, respectively) of sesamin, a lignan from sesame oil. After four weeks of ad libitum feeding, the rats were sacrificed and the concentrations of alpha- and gamma-tocopherols were measured in the plasma, livers, and lungs. Sesamin-feeding increased gamma-tocopherol and gamma-/alpha-tocopherol ratios in the plasma (P < 0.05), liver (P < 0.001), and lungs (P < 0.001). The increase was non-significant for alpha-tocopherol. Thus, sesamin appears to spare gamma-tocopherol in rat plasma and tissues, and this effect persists in the presence of alpha-tocopherol, a known competitor to gamma-tocopherol. This suggests that the bioavailability of gamma-tocopherol is enhanced in phenol-containing diets as compared with purified diets.
将六组大鼠喂食α-生育酚含量低但充足、γ-生育酚含量高的日粮。这六种日粮的区别仅在于芝麻素（一种来自芝麻油的木脂素）的含量（分别为0、0.25、0.5、1.0、2.0和4.0 g/kg）。自由采食四周后，处死大鼠并测定血浆、肝脏和肺中α-生育酚和γ-生育酚的浓度。喂食芝麻素可提高血浆（P < 0.05）、肝脏（P < 0.001）和肺（P < 0.001）中γ-生育酚和γ-/α-生育酚的比值。α-生育酚的增加不显著。因此，芝麻素似乎可在大鼠血浆和组织中节省γ-生育酚，并且在存在已知的γ-生育酚竞争物α-生育酚的情况下，这种作用仍然存在。这表明与纯化日粮相比，含酚日粮中γ-生育酚的生物利用度得到了提高。
