釉基质蛋白应用于两只犬自发性牙周病的疗效。

Efficacy of enamel matrix protein applied to spontaneous periodontal disease in two dogs.

作者信息

Watanabe Kazuhiro, Kikuchi Masahiro, Okumura Masahiro, Kadosawa Tsuyoshi, Fujinaga Toru

机构信息

Laboratory of Veterinary Surgery, Department of Veterinary Clinical Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Japan.

出版信息

J Vet Med Sci. 2003 Sep;65(9):1007-10. doi: 10.1292/jvms.65.1007.

DOI:10.1292/jvms.65.1007

PMID:14532695

Abstract

Enamel matrix protein (EMP) was applied for regeneration of periodontal tissue in 2 dogs with spontaneous periodontal disease. Case 1 had bony resorption around the root and root apex of the maxillary fourth premolars. Case 2 had vertical resorption of bone between the mandibular first and second molars. A flap was formed in the buccal gingiva, and EMP was applied onto the surface of the exposed root. One or 4 months postoperatively, increased bone level and clinical attachment were recognized. EMP was therefore suggested to be effective to induce regeneration of periodontal tissues in the cases with periodontal disease.

摘要

牙釉质基质蛋白（EMP）被应用于2只患有自发性牙周病的犬的牙周组织再生。病例1在上颌第四前磨牙的牙根及根尖周围存在骨质吸收。病例2在下颌第一和第二磨牙之间存在垂直性骨吸收。在颊侧牙龈形成一个瓣，并将EMP应用于暴露牙根的表面。术后1或4个月，观察到骨水平增加和临床附着增加。因此，提示EMP对诱导牙周病病例的牙周组织再生有效。