Vallancien Guy, Gupta Roby, Cathelineau Xavier, Baumert Hervé, Rozet François
Department of Urology, Institut Montsouris, Université Pierre et Marie Curie, Paris 75014, France.
J Urol. 2003 Nov;170(5):1838-40. doi: 10.1097/01.ju.0000091875.24816.6b.
We evaluated the feasibility of laparoscopic radical prostatectomy for recurrence after irradiation.
Since 2000, 7 patients with biological failure after irradiation (5 external beam radiation and 2 brachytherapy), and no metastasis on computerized tomography and bone scan underwent a transperitoneal laparoscopic radical prostatectomy according to the Montsouris technique. The left index finger was placed in the rectum to control the prostatorectal dissection. We call this procedure "finger assisted laparoscopy."
Average operating time was 190 minutes (range 170 to 210), average blood loss was 387 cc (range 50 to 1,100) and no patient was transfused. Bladder catheter was removed after an average of 13 days because of the slower tissue healing after irradiation. No death or intraoperative complication occurred. There was no conversion to open surgery. Average postoperative stay was 6.4 days. Average followup was 11.2 months. Of the 7 patients 5 are continent (no pad day or night) and 2 have stress incontinence. All patients are impotent. No patient had urethral stenosis or lymphocele. Prostate specific antigen is lower than 0.1 ng/ml in 5 patients and higher in 2.
Laparoscopic salvage radical prostatectomy after irradiation is feasible with no more morbidity than an open procedure. A longer followup is mandatory to evaluate its usefulness.
我们评估了腹腔镜根治性前列腺切除术治疗放疗后复发的可行性。
自2000年起,7例放疗后出现生物学失败的患者(5例接受外照射放疗,2例接受近距离放疗),计算机断层扫描和骨扫描未发现转移,按照蒙苏里技术接受了经腹腹腔镜根治性前列腺切除术。将左手食指放入直肠以控制前列腺直肠间隙的分离。我们将此手术称为“手指辅助腹腔镜手术”。
平均手术时间为190分钟(范围170至210分钟),平均失血量为387毫升(范围50至1100毫升),无患者接受输血。由于放疗后组织愈合较慢,平均13天后拔除膀胱导尿管。无死亡或术中并发症发生。无中转开放手术情况。平均术后住院时间为6.4天。平均随访时间为11.2个月。7例患者中,5例控尿(日夜均无需使用尿垫),2例有压力性尿失禁。所有患者均有阳痿。无患者发生尿道狭窄或淋巴囊肿。5例患者前列腺特异性抗原低于0.1纳克/毫升,2例患者高于此值。
放疗后腹腔镜挽救性根治性前列腺切除术是可行的,其发病率不高于开放手术。需要更长时间的随访以评估其有效性。