Paiba G A, Wilesmith J W, Evans S J, Pascoe S J S, Smith R P, Kidd S A, Ryan J B M, McLaren I M, Chappell S A, Willshaw G A, Cheasty T, French N P, Jones T W H, Buchanan H F, Challoner D J, Colloff A D, Cranwell M P, Daniel R G, Davies I H, Duff J P, Hogg R A T, Kirby F D, Millar M F, Monies R J, Nicholls M J, Payne J H
Centre for Epidemiology and Risk Analysis, Veterinary Laboratories Agency, Weybridge, New Haw, Surrey KT15 3NB.
Vet Rec. 2003 Sep 20;153(12):347-53. doi: 10.1136/vr.153.12.347.
During the decade to 1999, the incidence of human infections with the zoonotic pathogen verocytotoxin-producing Escherichia coli O157 (VTEC O157) increased in England and Wales. This paper describes the results of a survey of 75 farms to determine the prevalence of faecal excretion of VTEC O157 by cattle, its primary reservoir host, in England and Wales. Faecal samples were collected from 4663 cattle between June and December 1999. The prevalence of excretion by individual cattle was 4.2 per cent (95 per cent confidence interval [CI] 2.0 to 6.4) and 10.3 per cent (95 per cent CI 5.8 to 14.8) among animals in infected herds. The within-herd prevalence on positive farms ranged from 1.1 to 51.4 per cent. At least one positive animal was identified on 29 (38.7 per cent; 95 per cent CI 28.1 to 50.4) of the farms, including dairy, suckler and fattening herds. The prevalence of excretion was least in the calves under two months of age, peaked in the calves aged between two and six months and declined thereafter. The phage types identified most widely were 4, 34 and 2, which were each found on six of the 29 positive farms.
到1999年的十年间，人感染人畜共患病原体产志贺毒素大肠杆菌O157（VTEC O157）的发病率在英格兰和威尔士有所上升。本文描述了一项对75个农场的调查结果，以确定作为主要储存宿主的牛群中VTEC O157粪便排泄的流行情况，该调查在英格兰和威尔士开展。1999年6月至12月期间从4663头牛采集了粪便样本。个体牛的排泄流行率为4.2%（95%置信区间[CI] 2.0至6.4），在受感染牛群中的动物中为10.3%（95% CI 5.8至14.8）。阳性农场内的流行率在1.1%至51.4%之间。在29个（38.7%；95% CI 28.1至50.4）农场中至少发现了一头阳性动物，包括奶牛场、肉牛场和育肥场。排泄流行率在两个月龄以下的犊牛中最低，在两至六个月龄的犊牛中达到峰值，此后下降。最广泛鉴定出的噬菌体类型是4型、34型和2型，在29个阳性农场中的6个农场均发现了这几种类型。
